Exploring Cancer Drivers and Dependencies
- Speaker
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Scott W. Lowe, Ph.D.Chair, Geoffrey Beene Cancer Research Center, Memorial Sloan-Kettering Cancer Center
Presidential Lectures are a series of free public colloquia spotlighting groundbreaking research across four themes: neuroscience and autism science, physics, biology, and mathematics and computer science. These curated, high-level scientific talks feature leading scientists and mathematicians and are designed to foster discussion and drive discovery within the New York City research community. We invite those interested in these topics to join us for this weekly lecture series.
The human body contains gene networks that naturally inhibit tumor development. This defensive arsenal includes repairing damaged DNA, suppressing inflammation and triggering the self-destruction of cells.
In this lecture, Scott W. Lowe will discuss his lab’s work exploring how the genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response and create vulnerabilities that may be targeted therapeutically. He will outline how his team combines genetic, genomic and animal model approaches to comprehensively study cancer biology. He will also discuss tumor-suppressor gene networks and strategies to restore their function in advanced cancers.