From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others

Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.

The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide

Michelle C Rice, Jessica S Kim, Maria Imun, Sang Wun Jung, Chan Yoon Park, Rochelle W Lai, Casey R Barr, Jyung Mean Son, Kathleen Tor, Emmeline Kim, Ryan J Lu, Ilana Cohen, Bérénice Anath Benayoun and Changhan Lee

bioRxiv. posted 3 March 2023, 10.1101/2023.03.02.530691

[Abstract]

 

Delayed formation of neural representations of space in aged mice

Kelsey D. McDermott, M. Agustina Frechou, Jake T. Jordan, Sunaina S Martin, and J. Tiago Goncalves

bioRxiv posted 9 March 2023 doi:10.1101/2023.03.03.531021

[Abstract] [PDF]

 

Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer’s disease

Gilad Sahar Green, Masashi Fujita, Hyun-Sik Yang, Mariko Taga, Cristin McCabe, Anael Cain, Charles C. White, Anna K. Schmidtner, Yangling Wang, Aviv Regev, Vilas Menon, David A. Bennett, Naomi Habib, and Phillip De Jager

bioRxiv posted 9 March 2023 doi:10.1101/2023.03.07.531493

[Abstract] [PDF]

 

Hippocampal sclerosis of aging at post-mortem is evident on MRI more than a decade prior

Diana Ortega-Cruz, Juan Eugenio Iglesias, Alberto Rabano, and Bryan Strange

bioRxiv posted 10 March 2023 doi:10.1101/2023.03.08.531683

[Abstract] [PDF]

 

Hippocampal sclerosis of aging at post-mortem is evident on MRI more than a decade prior

Diana Ortega-Cruz, Juan Eugenio Iglesias, Alberto Rabano, and Bryan Strange

bioRxiv posted 10 March 2023 doi:10.1101/2023.03.08.531683

[Abstract] [PDF]

 

Antibody targeting of aging damaged isoDGR-protein doubles lifespan in a mouse model of chronic inflammation

Pazhanichamy Kalailingam, Khalilatul-Hanisah Mohd-Kahliab, SoFong Cam Ngan, Ranjith Iyappan, Evelin Melekh, Tian Lu, Gan Wei Zien, Bhargy Sharma, Tiannan Guo, Adam J MacNeil, Rebecca E. K. Macpherson, Evangelia Litsa Tsiani, Deborah D. O’Leary, Kah Leong Lim, I Hsin Su, Yong-Gui Gao, A Mark Richard, Raj N. Kalaria, Christopher P. Chen, Neil E. K. McCarthy and Siu Kwan Sze

bioRxiv. posted 12 March 2023, 10.1101/2023.03.11.532237

[Abstract]

 

Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation

Marius Marc-Daniel Mader, Alan Napole, Danei Wu, Yohei Shibuya, Alexa Scavetti, Aulden Foltz, Micaiah Atkins, Oliver Hahn, Yongjin Yoo, Ron Danziger, Christina Tan, Tony Wyss-Coray, Lawrence Stainman and Marius Wernig

bioRxiv. posted 12 March 2023, 10.1101/2023.03.10.532123

[Abstract]

 

Age-related brain mechanisms underlying short-term recognition of musical sequences: An EEG study

Marco Costa, Peter Vuust, Morten L Kringelbach, and Leonardo Bonetti

bioRxiv posted 13 March 2023 doi:10.1101/2023.03.12.532256

[Abstract] [PDF]

 

The effect of virtual visual scene inclination transitions on gait modulation in healthy young vs older adults – a virtual reality study

Amit Benady, Sean Zadik, Sharon Gilaie-Dotan, and Meir Plotnik

bioRxiv posted 14 March 2023 doi:10.1101/2023.03.14.532630

[Abstract] [PDF]

 

In search of a unifying theory of white matter aging: tract morphometry-microstructure relationships

Tyler D. Robinson, Yutong L. Sun, Paul Chang, and J. Jean Chen

bioRxiv posted 15 March 2023 doi:10.1101/2023.03.14.532658

[Abstract] [PDF]

 

Uneven terrain versus dual-task walking: differential challenges imposed on walking behavior in older adults are predicted by cognitive and sensorimotor function

Valay A Shah, Yenisel Cruz-Alemida, Arkaprava Roy, Erta Cenko, Ryan J Downey, Daniel P Ferris, Chris J Hass, Patricia A Reuter-Lorenz, David J Clark, Todd M Manini, and Rachael D Seidler

bioRxiv posted 15 March 2023 doi:10.1101/2023.03.14.531779

[Abstract] [PDF]

 

Vessel Density Mapping of Cerebral Small Vessels on 3D High Resolution Black Blood MRI

Mona Sharifi Sarabi, Samantha Ma, Kay Jann, John Ringman, Danny JJ Wang, and Yonggang Shi

bioRxiv posted 21 March 2023 doi:10.1101/2023.03.18.533300

[Abstract] [PDF]

 

Mouse Adapted SARS-CoV-2 Model Induces “Long-COVID” Neuropathology in BALB/c Mice

Timothy E. Gressett, Sarah R. Leist, Saifudeen Ismael, Grant Talkington, Kenneth H. Dinnon, Ralph S. Baric, and Gregory Bix

bioRxiv posted 20 March 2023 doi:10.1101/2023.03.18.533204

[Abstract] [PDF]

 

TREM2-dependent senescent microglia conserved in aging and Alzheimer’s disease

Noa Rachmian, Sedi Medina, Ulysse Cherqui, Hagay Akiva, Daniel Deitch, Dunya Edilbi, Tommaso Croese, Tomer Meir Salame, Javier Maria Peralta Ramos, Liora Cahalon, Valery Krizhanovsky, and Michal Schwartz

bioRxiv posted 21 March 2023 doi:10.1101/2023.03.20.533401

[Abstract] [PDF]

 

Age differences in neural distinctiveness during memory retrieval versus reinstatement

Claire Pauley, Malte Kobelt, Markus Werkle-Bergner, and Myriam C. Sander

bioRxiv posted 21 March 2023 doi:10.1101/2023.03.21.533591

[Abstract] [PDF]

 

SARS-CoV-2 infection induces dopaminergic neuronal loss in midbrain organoids during short and prolonged cultures

Javier Jarazo, Eveline Santos da Silva, Enrico Glaab, Danielle Perez-Bercoff, and Jens Christian Schwamborn

bioRxiv posted 21 March 2023 doi:10.1101/2023.03.20.533485

[Abstract] [PDF]

 

Brain functional characterization of response-code conflict in dual-tasking and its modulation by age

Lya Katarina Paas Oliveros, Edna C. Cieslik, Aleks Pieczykolan, Rachel N. Pläschke, Simon B. Eickhoff, and Robert Langner

bioRxiv posted 23 March 2023 doi:10.1101/2023.03.21.533669

[Abstract] [PDF]

 

Two long-axis dimensions of hippocampal cortical integration support memory function across the adult lifespan

Kristin Nordin, Robin Pedersen, Farshad Falahati, Jarkko Johansson, Filip Grill, Micael Andersson, Saana Korkki, Lars Backman, Andrew Zalesky, Anna Rieckmann, Lars Nyberg, and Alireza Salami

bioRxiv posted 25 March 2023 doi:10.1101/2023.03.24.534115

[Abstract] [PDF]

 

Age-related variability in network engagement during music listening

Sarah EM Faber, Alexander G Belden, Psyche Loui, and Anthony Randal McIntosh

bioRxiv posted 25 March 2023 doi:10.1101/2023.03.24.534123

[Abstract] [PDF]

 

Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

Ching-Chieh Chou, Ryan Vest, Miguel A Prado, Joshua Wilson-Grady, Joao A Paulo, Yohei Shibuya, Patricia Moran-Losada, Ting-Ting Lee, Jian Luo, Steven P Gygi, Jeffery W Kelly, Dan Finley, Marius Wernig, Tony Wyss-Coray and Judith Frydman

bioRxiv. posted 27 March 2023, 10.1101/2023.03.27.534444

[Abstract]

 

Neuromolecular interactions guiding homeostatic mechanisms underlying healthy ageing: A view from computational microscope

Suman Saha, Priyanka Chakraborty, Amit Naskar, Dipanjan Roy, and Arpan Banerjee

bioRxiv posted 28 March 2023 doi:10.1101/2023.03.27.534486

[Abstract] [PDF]

 

Fornix fractional anisotropy mediates the association between Mediterranean diet adherence and memory four years later in older adults without dementia

Adriana L. Ruiz-Rizzo, Kathrin Finke, Jessica S. Damoiseaux, Claudia Bartels, Katharina Buerger, Nicoleta Carmen Cosma, Peter Dechent, Laura Dobisch, Michael Ewers, Klaus Fliessbach, Ingo Frommann, Wenzel Glanz, Doreen Goerss, Stefan Hetzer, Enise I. Incesoy, Daniel Janowitz, Ingo Kilimann, Christoph Laske, Debora Melo van Lent, Matthias H.J. Munk, Oliver Peters, Josef Priller, Alfredo Ramirez, Ayda Rostamzadeh, Nina Roy, Klaus Scheffler, Anja Schneider, Annika Spottke, Eike Jakob Spruth, Stefan Teipel, Michael Wagner, Jens Wiltfang, Renat Yakupov, Frank Jessen, Emrah Duezel, Robert Perneczky, and Boris-Stephan Rauchmann

bioRxiv posted 31 March 2023 doi:10.1101/2023.03.31.534758

[Abstract] [PDF]

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