From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others
Endothelial cell derived microvesicles modulate cerebrovascular and brain aging via miR-17-5p and serve as potential biomarkers for vascular aging
Huiting Zhang, Zi Xie, Yuhui Zhao, Yanyu Chen, Xiaobing Xu, Ye Ye, Yuping Yang, Wangtao Zhong, Bin Zhao, and Xiaotang Ma
bioRxiv posted 3 February 2023
Cognitive reserve counteracts typical neural activity changes related to ageing
Jesus Cespon, Irina Chupina, and Manuel Carreiras
bioRxiv posted 3 February 2023
Region-specific impact of aging on cortical myelination and thickness
Arianna Brancaccio, Davide Tabarelli, and Paolo Belardinelli
bioRxiv posted 4 February 2023
Cochlear dysfunction as an early biomarker for cognitive decline in normal hearing and mild hearing loss
Vicente Medel, Paul H. Delano, Chama Belkhiria, Alexis Leiva, Cristina De Gatica, Victor Vidal, Carlos F. Navarro, Simon San Martin, Melissa Martinez, Christine Gierke, Ximena Garcia, Mauricio Cerda, Rodrigo Vergara, Carolina Delgado, and Gonzalo Farias
bioRxiv posted 5 February 2023
Healthy ageing effects on implicit auditory memory: from encoding to 6-month retention
Roberta Bianco, Edward T. R. Hall, Marcus T. Pearce, and Maria Chait
bioRxiv posted 10 February 2023
Healthy ageing effects on implicit auditory memory: from encoding to 6-month retention
Roberta Bianco, Edward T. R. Hall, Marcus T. Pearce, and Maria Chait
bioRxiv posted 10 February 2023
Aging with TBI vs. Aging: 6-month temporal profiles for neuropathology and astrocyte activation converge in behaviorally relevant thalamocortical circuitry of male and female rats
Zackary Sabetta, Gokul Krishna, Tala Curry, P David Adelson, and Theresa Currier Thomas
bioRxiv posted 7 February 2023
Neuronal properties of pyramidal cells in lateral prefrontal cortex of the aging rhesus monkey brain are associated with performance deficits on spatial working memory but not executive function.
Tara L Moore, Maria Medalla, Sara Ibanez, Klaus Wimmer, Chromewell Mojica, Ronald J Killiany, Mark B Moss, Jennifer I Luebke, and Douglas L Rosene
bioRxiv posted 8 February 2023
Brain tissue cerebrospinal fluid fraction increases quadratically in normal aging
Liangdong Zhou, Yi Li, Elizabeth M. Sweeney, Xiuyuan H. Wang, Amy Kuceyeski, Gloria C. Chang, Yi Wang, Jana Ivanidze, Susan A. Gauthier, Mony J. de Leon, and Thanh D. Nguyen
bioRxiv posted 10 February 2023
Atrophic astrocytes in aged marmosets present tau hyperphosphorylation, RNA oxidation, and DNA fragmentation
Juan de Dios Rodriguez-Callejas, Eberhard Fuchs, and Claudia Perez-Cruz
bioRxiv posted 10 February 2023
Smooth pursuit eye movements contribute to anticipatory force control during mechanical stopping of moving objects
Oindrila Sinha, Shirin Madarshahian, Ana Maria Gomez-Granados, Morgan L Paine, Isaac Kurtzer, and Tarkeshwar Singh
bioRxiv posted 13 February 2023
The iron-dopamine D1 coupling modulates neural signatures of working memory across adulthood
Jonatan Gustavsson, Jarkko Johansson, Farshad Falahati, Micael Andersson, Goran Papenberg, Bárbara Avelar-Pereira, Lars Bäckman, Grégoria Kalpouzos, and Alireza Salami
bioRxiv posted 10 February 2023
In vivo Locus Coeruleus activity while awake is associated with REM sleep quality in healthy older individuals
Ekaterina Koshmanova, Alexandre Berger, Elise Beckers, Islay Campbell, Nasrin Mortazavi, Roya Sharifpour, Ilenia Paparella, Fermin Balda, Christian Berthomier, Christian Degueldre, Eric Salmon, Laurent Lamalle, Christine Bastin, Maxime Van Egroo, Christophe Phillips, Pierre Maquet, Fabienne Collette, Vincenzo Muto, Daphne Chylinski, Heidi Jacobs, Puneet Talwar, Siya Sherif, and Gilles Vandewalle
bioRxiv posted 12 February 2023
Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation
Paul Shin, Qi Pian, Hidehiro Ishikawa, Gen Hamanaka, Emiri T Mandeville, Guo Shuzhen, Fu Buyin, Mohammed Alfadhel, Srinivasa Rao Allu, Ikbal Sencan-Egilmez, Baoqiang Li, Chongzhao Ran, Sergei A Vinogradov, Cenk Ayata, Eng Lo, Ken Arai, Anna Devor, and Sava Sakadzic
bioRxiv posted 14 February 2023
Linking structural and functional changes during aging using multilayer brain network analysis
Gwendolyn Jauny, Mite Mijalkov, Anna Canal-Garcia, Giovanni Volpe, Joana.B. Pereira, Francis Eustache, and Thomas T Hinault
bioRxiv posted 15 February 2023
Slope of the power spectral density flattens at low frequencies (<150 Hz) with healthy aging but also steepens at higher frequency (>200 Hz) in human electroencephalogram
Srishty Aggarwal and Supratim Ray
bioRxiv posted 15 February 2023
Signaling from the C. elegans Hypodermis Non-autonomously Facilitates Short-term Associative Memory
Shiyi Zhou, Yan-Ping Zhang, Rachel Kaletsky, Erik Toraason, Wenhong Zhang, Meng-Qiu Dong and Coleen T. Murphy
bioRxiv. posted 16 February 2023
Mapping Sleep’s Oscillatory Events as a Biomarker of Alzheimer’s Disease
Rachelle L Pulver, Eugene Kronberg, Lindsey M Medenblik, Vitaly O Kheyfets, Alberto R Ramos, David M Holtzman, John C Morris, Cristina D Toedebusch, Stefan H Sillau, Brianne M Bettcher, Brendan P Lucey, and Brice V McConnell
bioRxiv posted 16 February 2023
Age-related changes in network controllability are mitigated by redundancy in large-scale brain networks
William C Stanford, Peter J Mucha, and Eran Dayan
bioRxiv posted 18 February 2023
A long-term ketogenic diet in young and aged rats has dissociable effects on prelimbic cortex and CA3 ensemble activity
Abbi R Hernandez, Maya E Barrett, Katelyn N Lubke, Andrew Maurer and Sara N Burke
bioRxiv. posted 19 February 2023
Is resting state fMRI better than individual characteristics at predicting cognition?
Amir Omidvarnia, Leonard Sasse, Daouia I. Larabi, Federico Raimondo, Felix Hoffstaedter, Jan Kasper, Juergen Dukart, Marvin Petersen, Bastian Cheng, Goetz Thomalla, Simon B. Eickhoff, and Kaustubh R. Patil
bioRxiv posted 21 February 2023
Education differentiates cognitive performance and resting state fMRI connectivity in healthy aging
Sonia Montemurro, Nicola Filippini, Giulio Ferrazzi, Dante Mantini, Giorgio Arcara, and Marco Marino
bioRxiv posted 22 February 2023
Age-related differences in fMRI subsequent memory effects are directly linked to local grey matter volume differences
Jasmin M. Kizilirmak, Joram Soch, Anni Richter, and Björn Hendrik Schott
bioRxiv posted 23 February 2023
Cellular and molecular signatures of motherhood in the adult and ageing brain
Paula Duarte Guterman, Jennifer Richard, Stephanie Lieblich, Rand Eid, Yvonne Lamers, and Liisa Galea
bioRxiv posted 24 February 2023
Resting-state fMRI signals contain spectral signatures of local hemodynamic response timing
Sydney M. Bailes, Daniel E. P. Gomez, Beverly Setzer and Laura D. Lewis
bioRxiv. posted 26 January 2023
Lifespan Changes in Brain Structure and Cognitive Performance Associated with Normal Aging in Mice
Kevan P Clifford, Amy Miles, Thomas D Prevot, Keith A Misquitta, Jacob Ellegood, Jason P Lerch, Etienne Sibille, Yuliya S Nikolova, and Mounira Banasr
bioRxiv posted 27 February 2023
Sex-dimorphic regulation of extracellular matrix genes in mouse bone marrow neutrophils
Cassandra J. McGill, Collin Y. Ewald and Bérénice A. Benayoun
bioRxiv. posted 27 February 2023
How Healthy Older Adults Enact Lateral Maneuvers While Walking
David M. Desmet, Meghan E. Kazanski, Joseph P. Cusumano, and Jonathan B. Dingwell
bioRxiv posted 27 February 2023
The influence of generativity on purpose in life is mediated by social support and moderated by prefrontal connectivity between the VMPFC and DLPFC in older adults at risk for Alzheimer’s disease
Caitlin S. Walker, Linda Li, and Maiya R. Geddes
bioRxiv posted 27 February 2023
EiDA: A lossless approach for the dynamic analysis of connectivity patterns in signals; application to resting state fMRI of a model of ageing
Giuseppe de Alteriis, Eilidh MacNicol, Fran Hancock, Diana Cash, Paul Expert, and Federico E Turkheimer
bioRxiv posted 28 February 2023
Normative Modeling of Brain Morphometry Across the Lifespan using CentileBrain: Algorithm Benchmarking and Model Optimization
Ruiyang Ge, Yuetong Yu, Yi Xuan Qi, Yunan Vera Fan, Shiyu Chen, Chuntong Gao, Shalaila S Haas, Amirhossein Modabbernia, Faye New, Ingrid Agartz, Philip Asherson, Rosa Ayesa-Arriola, Nerisa Banaj, Tobias Banaschewski, Sarah Baumeister, Alessandro Bertolino, Dorret I Boomsma, Stefan Borgwardt, Josiane Bourque, Daniel Brandeis, Alan Breier, Henry Brodaty, Rachel M Brouwer, Randy Buckner, Jan K Buitelaar, Dara M Cannon, Xavier Caseras, Simon Cervenka, Patricia J Conrod, Benedicto Crespo-Facorro, Fabrice Crivello, Eveline A Crone, Liewe de Haan, Greig I de Zubicaray, Annabella Di Giorgio, Susanne Erk, Simon E Fisher, Barbara Franke, Thomas Frodl, David C Glahn, Dominik Grotegerd, Oliver Gruber, Patricia Gruner, Raquel E Gur, Ruben C Gur, Ben J Harrison, Sean N Hatton, Ian Hickie , Fleur M Howells, Hilleke E Hulshoff Pol, Chaim Huyser, Terry L Jernigan, Jiyang Jiang, John A Joska, René S Kahn, Andrew J Kalnin, Nicole A Kochan, Sanne Koops, Jonna Kuntsi, Jim Lagopoulos, Luisa Lazaro, Irina S Lebedeva, Christine Lochner, Nicholas G Martin, Bernard Mazoyer, Brenna C McDonald, Colm McDonald, Katie L McMahon, Tomohiro Nakao, Lars Nyberg, Fabrizio Piras, Maria J Portella, Jiang Qiu, Joshua L Roffman, Perminder S Sachdev, Theodore D Satterthwaite, Andrew J Saykin, Gunter Schumann, Carl M Sellgren, Kang Sim, Jordan W Smoller, Jair Soares, Iris E Sommer, Gianfranco Spalletta, Dan J Stein, Christian K Tamnes, Sophia I Thomopolous, Alexander S Tomyshev, Diana Tordesillas-Gutiérrez, Julian N Trollor, Dennis van ’t Ent, Odile A van den Heuvel, Theo GM van Erp, Neeltje EM van Haren, Daniela Vecchio, Dick J Veltman, Henrik Walter, Yang Wang, Bernd Weber, Dongtao Wei, Wei Wen, Lars T Westlye, Lara M Wierenga, Steven CR Williams, Margaret J Wright, Sa rah Medland, Mon-Ju Wu, Neda Jahanshad, Paul M Thompson and Sophia Frangou
bioRxiv. posted 31 January 2023