From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others
A brain-wide form of presynaptic active zone plasticity orchestrates resilience to brain aging in Drosophila
Sheng Huang, Chengji Piao, Christine Beuschel, and Stephan J Sigrist
bioRxiv posted 2 July 2022
COVID-19 Neuropathology: evidence for SARS-CoV-2 invasion of Human Brainstem Nuclei
Aron Emmi, Stefania Rizzo, Luisa Barzon, Michele Sandre, Elisa Carturan, Alessandro Sinigaglia, Silvia Riccetti, Mila della Barbera, Rafael Boscolo-Berto, Patrizia Cocco, Veronica Macchi, Angelo Antonini, Monica De Gaspari, Cristina Basso, Raffaele De Caro, and Andrea Porzionato
bioRxiv posted 5 July 2022
Brain Network Architecture Constrains Age-related Cortical Thinning
Marvin Petersen, Felix L. Naegele, Carola Mayer, Max Schell, D. Leander Rimmele, Elina Petersen, Simone Kuehn, Juergen Gallinat, Uta Hanning, Jens Fiehler, Raphael Twerenbold, Christian Gerloff, Goetz Thomalla, and Bastian Cheng
bioRxiv posted 10 July 2022
Age-dependent attentional style and pupil-linked arousal regulate the reportability of spontaneous mental states
Matthieu Koroma, Aurele Robert de Beauchamp, Sepehr Mortaheb, Paradeisios Alexandros Boulakis, Christine Bastin, and Athena Demertzi
bioRxiv posted 10 July 2022
Effects of age and sex on dendritic D2 autoreceptor inhibition in substantia nigra dopamine neurons
Eva Troyano-Rodriguez, Kylie Handa, Sarah Y Branch, and Michael J Beckstead
bioRxiv posted 11 July 2022
Hippocampal microstructure, but not macrostructure, mediates age differences in episodic memory
Kirolos Ibrahim and Ilana Bennett
bioRxiv posted 13 July 2022
Hippocampal and caudate network specificity is altered in older adults
Michael V Freedberg
bioRxiv posted 14 July 2022
Decline of intrinsic cerebrospinal fluid outflow in healthy humans with age detected by non-contrast spin-labeling MRI
Vadim Malis, Won C Bae, Asako Yamamoto, Linda K McEvoy, Marin A McDonald, and Mitsue Miyazaki
bioRxiv posted 18 July 2022
Neurophysiological markers of successful learning in healthy aging
Dawid Strzelczyk, Tzvetan Popov, Simon Kelly, and Nicolas Langer
bioRxiv posted 19 July 2022
X chromosome factor Kdm6a enhances memory independent of its demethylase function in the aging XY male brain
Cayce K. Shaw, Samira Abdulai-Saiku, Francesca Marino, Dan Wang, Emily J. Davis, Barbara Panning, and Dena B. Dubal
bioRxiv posted 19 July 2022
Superficial white matter across the lifespan: volume, thickness, change, and relationship with cortical features
Kurt Schilling, Derek B Archer, Francois Rheault, Ilwoo Lyu, Yuankai Huo, Leon Y Cai, Silvia Bunge, Kevin S. Weiner, John C Gore, Adam W Anderson, and Bennett A Landman
bioRxiv posted 21 July 2022
Age-dependent NMDA receptor function is regulated by the Amyloid Precursor Protein
Joana Rajao-Saraiva, Mariana Temido-Ferreira, Joana E Coelho, Aurore Ribera, Sebastien Moreno, Michael Willem, Helene Marie, Luisa V. Lopes, and Paula A Pousinha
bioRxiv posted 21 July 2022
Sex differences in default mode network connectivity in healthy aging adults
Bronte Ficek-Tani, Corey Horien, Suyeon Ju, Nancy Li, Cheryl Lacadie, Xilin Shen, Dustin Scheinost, Robert T Constable, and Carolyn A Fredericks
bioRxiv posted 22 July 2022
Large-scale in vivo CRISPR screens identify SAGA complex members as a key regulators of HSC lineage commitment and aging
Michael S Haney, Archana Shankar, Ian Hsu, Masashi Miyauchi, Robert Palovics, Hwei Minn Khoo, Kyomi J Igarashi, Joydeep Bhadury, Christy Munson, Paul K Mack, Tze-Kai Tan, Tony Wyss-Coray, Hiromitsu Nakauchi and Adam C Wilkinson
bioRxiv. posted 22 July 2022
Brain-based Lifespan Trajectories of Social Cognition: From Resting-state fMRI Perspective
Wei Fan and Zhixiong Yan
bioRxiv posted 23 July 2022
Poor sensitivity of iPSC-derived neural progenitors and glutamatergic neurons to SARS-CoV-2
Marija Zivaljic, Mathieu Hubert, Ludivine Grzelak, Giulia Sansone, Uwe Maskos, and Olivier Schwartz
bioRxiv posted 25 July 2022
Unbiased Classification of the Human Brain Proteome Resolves Distinct Clinical and Pathophysiological Subtypes of Cognitive Impairment
Lenora A Higginbotham, E Kathleen Carter, Eric B Dammer, Rafi U Haque, Erik C.B. Johnson, Duc Duong, Luming Yin, Phillip L De Jager, David A Bennett, James J Lah, Allan I Levey, and Nicholas T Seyfried
bioRxiv posted 25 July 2022
Cognitive aging and categorical representations in visual working memory
Cherie Zhou and Monicque M. Lorist
bioRxiv posted 25 July 2022
Global signal topography in the human brain differs systematically across the lifespan
Jason Nomi, Danilo Bzdok, Jingwei Li, Taylor Bolt, Salome Kornfeld, Zach Goodman, B.T. Thomas Yeo, R. Nathan Spreng, and Lucina Uddin
bioRxiv posted 27 July 2022
Neural contributions to reduced fluid intelligence across the adult lifespan
Daniel J Mitchell, Alexa LS Mousley, Meredith A Shafto, Cam-CAN, and John Duncan
bioRxiv posted 27 July 2022
Brain structural covariances in the ageing brain in the UK Biobank
Chao Dong, Anbu Thalamuthu, Jiyang Jiang, Karen A. Mather, Perminder S. Sachdev, and Wei Wen
bioRxiv posted 28 July 2022
Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation
Ryszard S. Gomolka, Lauren M. Hablitz, Humberto P. Mestre, Michael Gianetto, Ting Du, Natalie L. Hauglund, Lulu Xie, Weiguo Peng, Paula M. Martinez, Maiken Nedergaard, and Yuki Mori
bioRxiv posted 29 July 2022
Linguistic speech processing decreases with advancing age
Marlies Gillis, Jill Kries, Maaike Vandermosten, and Tom Francart
bioRxiv posted 29 July 2022
Functional connectivity between interoceptive brain regions is associated with distinct health-related domains – a population-based neuroimaging study
Alexander Luettich, Carolin Sievers, Fidel Alfaro Almagro, Micah Allen, Saad Jbabdi, Stephen Smith, and Kyle Pattinson
bioRxiv posted 29 July 2022
Sex and BDNF Val66Met Polymorphism matter for exercise-induced increase in neurogenesis and cognition in middle-aged mice
Dannia Islas, Tallinn FL Splinter, Muna Ibrahim, Natasha Black, Sarah Wong, Teresa Liu-Ambrose, Cindy K Barha and Liisa Galea
bioRxiv. posted 31 July 2022