From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others

Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.

Preserved cognition in elderly with intact rhinal cortex

Farshid Sepehrband, Kirsten Mary Lynch, Andrea Sotelo Gasperi, Michael Bienkowski, Xinhui Wang, Helena C Chui, and Arthur W. Toga

bioRxiv posted 1 June 2022

[Abstract] [PDF]

 

Connectome-based predictive modeling of cognitive reserve using task-based functional connectivity

Rory Boyle, Michael Connaughton, Eimear McGlinchey, Silvin P Knight, Céline De Looze, Daniel Carey, Yaakov Stern, Ian H Robertson, Rose Anne Kenny, and Robert Whelan

bioRxiv posted 2 June 2022

[Abstract] [PDF]

 

Age exacerbates SARS-CoV-2-induced blood-brain barrier leakage and neuropsychiatric dysfunction

Seshadri Bhargava Niladhuri, Guliz Otkiran Clare, KaReisha F. Robinson, Jacob Class, Ali A Almousawi, Troy N Trevino, Felecia Marottoli, Leon M. Tai, Justin ME Richner, and Sarah E Lutz

bioRxiv posted 3 June 2022

[Abstract] [PDF]

 

Ensemble-specific deficit in neuronal intrinsic excitability in aged mice

Lingxuan Chen, Taylor Francisco, Austin Baggetta, Steve Ramirez, Roger Clem, Tristan Shuman, and Denise Jade Cai

bioRxiv posted 3 June 2022

[Abstract] [PDF]

 

Interpretable deep learning of myelin histopathology in age-related cognitive impairment

Andrew T. McKenzie, Gabriel Marx, Daniel Koenigsberg, Mary Sawyer, Megan A. Iida, Jamie M. Walker, Timothy E. Richardson, Gabriele Campanella, Johannes Attems, Ann C. McKee, Thor D. Stein, Thomas J. Fuchs, Charles L. White, The PART Working Group, Kurt Farrell and John F. Crary

bioRxiv. posted 6 June 2022

[Abstract]

 

Short superficial white matter and aging: a longitudinal multi-site study of 1,293 subjects and 2,711 sessions

Kurt G Schilling, Derek B Archer, Fang-Cheng Yeh, Francois Rheault, Leon Y Cai, Andrea Shafer, Susan M Resnick, Timothy Hohman, Angela Jefferson, Adam W Anderson, Hakmook Kang, and Bennett A Landman

bioRxiv posted 6 June 2022

[Abstract] [PDF]

 

Ifit2 regulates murine-coronavirus spread to the spinal cord white matter and its associated myelin pathology

Madhav Sharma, Debanjana Chakravarty, Ajay Zalavadia, Amy Burrows, Patricia Rayman, Nikhil Sharma, Lawrence C. Kenyon, Cornelia Bergmann, Ganes C. Sen, and Jayasri Das Sarma

bioRxiv posted 7 June 2022

[Abstract] [PDF]

 

SARS-CoV-2 spike protein induces long-term TLR4-mediated synapse and cognitive loss recapitulating Post-COVID syndrome

Fabricia Lima Fontes-Dantas, Gabriel G Fernandes, Elisa G. Gutman, Emanuelle V. De Lima, Leticia S. Antonio, Mariana B. Hammerle, Hannah P. Mota-Araujo, Lilian C. Colodeti, Suzana M. B. Araujo, Talita N. da Silva, Larissa A. Duarte, Andreza L. Salvio, Karina L. Pires, Luciane A. A. Leon, Claudia C. F. Vasconcelos, Luciana Romao, Luiz E.B. Savio, Jerson L. Silva, Robson da Costa, Julia R. Clarke, Andrea T. Da Poian, Soniza V. Alves-Leon, Giselle F. Passos, and Claudia P. Figueiredo

bioRxiv posted 10 June 2022

[Abstract] [PDF]

 

Age-related learning and working memory impairment in the common marmoset

Courtney Glavis-Bloom, Casey R Vanderlip, and John H Reynolds

bioRxiv posted 9 June 2022

[Abstract] [PDF]

 

Neurometabolic timecourse of healthy aging

Tao Gong, Steve C.N. Hui, Helge J Zollner, Mark Britton, Yulu Song, Yufan Chen, Aaron T Gudmundson, Kathleen E Hupfeld, Saipavitra Murali-Manohar, Eric Porges, Georg Oeltzschner, Weibo Chen, Guangbin Wang, and Richard A.E. Edden

bioRxiv posted 10 June 2022

[Abstract] [PDF]

 

Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts

Ricardo Castro-Hernandez, Tea Berulava, Mariia Metelova, Robert Epple, Tonatiuh Pena Centeno, M. Sadman Sakib, Susanne Burkhart, Nomchil Ninov, Katherine E. Bohnsack, Markus T. Bohnsack, Ivana Dellale, and Andre Fischer

bioRxiv posted 10 June 2022

[Abstract] [PDF]

 

The relationship between response dynamics and the formation of confidence varies across the lifespan

Helen Overhoff, Yiu Hong Ko, Gereon Rudolf Fink, Jutta Stahl, Peter Horst Weiss, Stefan Bode, and Eva Niessen

bioRxiv posted 16 June 2022

[Abstract] [PDF]

 

Sex-specific age-related changes in excitatory and inhibitory intra-cortical circuits in mouse primary auditory cortex

Binghan Xue, Joseph P-Y Kao, and Patrick O Kanold

bioRxiv posted 17 June 2022

[Abstract] [PDF]

 

The meningeal transcriptional response to traumatic brain injury and aging

Ashley Catherine Bolte, Daniel A Shapiro, Arun B Dutta, Wei Feng Ma, Katherine R Bruch, Ana Royo Marco, and John R Lukens

bioRxiv posted 17 June 2022

[Abstract] [PDF]

 

Astrocyte Autophagy Response Upon Neuronal Cilia Loss in the Aging Brain

Laura de las Heras-Garcia and Olatz Pampliega

bioRxiv posted 17 June 2022

[Abstract] [PDF]

 

Purely STDP-based assembly dynamics: stability, learning, overlaps, drift and aging

Paul Manz and Raoul-Martin Memmesheimer

bioRxiv posted 21 June 2022

[Abstract] [PDF]

 

Probing Multiple Algorithms to Calculate Brain Age: Examining Reliability, Relations with Demographics, and Predictive Power

Eva Bacas, Isabella Kahhalé, Pradeep Raamana, Apurvaa Anand, Julian Pablo, and Jamie Hanson

bioRxiv posted 21 June 2022

[Abstract] [PDF]

 

Increased levels of circulating neurotoxic metabolites in patients with mild Covid19

Estibaliz Santiago-Mujika, Kevin Heinrich, Sonia George, Colt D Capan, Cameron Forton, Zachary Madaj, Amanda R Burmeister, Matthew Sims, Andrew Pospisilik, Patrik Brundin, Stewart F Graham, and Lena Brundin

bioRxiv posted 24 June 2022

[Abstract] [PDF]

 

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