From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others
Preserved executive control in ageing: The role of literacy experience
Ana I. Perez, Georgia Fotiadou, and Ianthi M. Tsimpli
bioRxiv posted 1 May 2022
A resource for generating and manipulating human microglial states in vitro
Michael-John Dolan, Martine Therrien, Sasa Jereb, Tushar Kamath, Trevor Atkeson, Samuel Marsh, Aleksandrina Goeva, Neal Lojek, Sarah Murphy, Cassandra White, Julia Joung, Bingxu Liu, Francesco Limone, Kevin Eggan, Nir Hacohen, Bradley Bernstein, Christopher Glass, Ville Leinonen, Mathew Blurton-Jones, Feng Zhang, Charles B. Epstein, Evan Macosko, and Beth Stevens
bioRxiv posted 2 May 2022
A pro-oxidant combination of resveratrol and copper down-regulates multiple biological hallmarks of ageing and neurodegeneration
Kavita Pal, Raghuram Venkata Gorantla, Jenevieve D’souza, Sushma Mehta, Vishalkumar Jadhav, Alfina Shaikh, Bhagyeshri Rane, Harshali Tandel, Dipali Kondhalkar, Shahid Chaudhary, and Indraneel Mittra
bioRxiv posted 4 May 2022
A hippocampal-anterior thalamic circuit associated with learning rate in ageing
Darya Frank, Marta Garo-Pascual, Pablo Alejandro Reyes Velasquez, Belen Frades, Noam Peled, Linda Zhang, and Bryan Strange
bioRxiv posted 4 May 2022
Characterizing ketamine-induced dissociation using human intracranial neurophysiology: brain dynamics, network activity, and interactions with propofol
Fangyun Tian, Laura D. Lewis, David W. Zhou, Gustavo Balanza Villegas, Angelique C. Paulk, Rina Zelmann, Noam Peled, Daniel Soper, Laura A. Santa Cruz Mercado, Robert A. Peterfreund, Linda S. Aglio, Emad N. Eskandar, G Rees Cosgrove, Ziv M. Williams, Robert M. Richardson, Emery N. Brown, Oluwaseun Akeju, Sydney S. Cash and Patrick L. Purdon
bioRxiv posted 4 May 2022
Evaluation of Cognitive Function in the Dog Aging Project: Associations with Baseline Canine Characteristics
Sarah Yarborough, Annette Fitzpatrick, Stephen Schwartz and Dog Aging Project Consortium
bioRxiv posted 5 May 2022
Dynamic regulation of neural variability during working memory reflects dopamine, functional integration, and decision-making
Douglas D. Garrett, Niels A. Kloosterman, Samira Epp, Vivien Chopurian, Julian Quirin Kosciessa, Leonhard Waschke, Alex Skowron, James Shine, Alistair Perry, Alireza Salami, Anna Rieckmann, Goran Papenberg, Anders Wahlin, Nina Karalija, Micael Andersson, Katrine Ricklund, Martin Lovden, Lars Bäckman, Lars Nyberg and Ulman Lindenberger
bioRxiv posted 5 May 2022
Common genetic variants in CHRNA5 alter β-amyloid neuropathology and highlight chandelier cells in human aging and Alzheimer’s disease
Jonas Rybnicek, Yuxiao Chen, Milos Milic, JoAnne McLaurin, Phillip De Jager, Julie A Schneider, Yanling Wang, David A Bennett, Shreejoy Tripathy, Daniel Felsky, and Evelyn K Lambe
bioRxiv posted 5 May 2022
Heart Rate Variability Covaries with Amygdala Functional Connectivity During Voluntary Emotion Regulation
Emma Tupitsa, Ifeoma Egbuniwe, William K. Lloyd, Marta Puertollano, Birthe Macdonald, Karin Joanknecht, Michiko Sakaki, and Carien M. van Reekum
bioRxiv posted 6 May 2022
Entorhinal-hippocampal circuit integrity is related to mnemonic discrimination and amyloid-β pathology in older adults
Jenna N. Adams, Soyun Kim, Batool Rizvi, Mithra Sathishkumar, Lisa Taylor, Alyssa L. Harris, Abanoub Mikhail, David B. Keator, Liv McMillan, and Michael A. Yassa
bioRxiv posted 10 May 2022
Age-related reorganization of functional network architecture for language processing
Sandra Martin, Kathleen Anne Williams, Dorothee Saur, and Gesa Hartwigsen
bioRxiv posted 10 May 2022
The structure of anticorrelated networks in the human brain
Endika Martinez, Antonio Jimenez, Sebastiano Stramaglia, and Jesus Cortes
bioRxiv posted 20 May 2022
Changes of oscillatory and aperiodic neuronal activity in working memory following anaesthesia: a prospective observational study
Janna D Lendner, Ulrich Harler, Jonathan Daume, Andreas K Engel, Christian Zoellner, Till R Schneider, and Marlene Fischer
bioRxiv posted 13 May 2022
Medial temporal lobe structure, mnemonic and perceptual discrimination in healthy older adults and those at risk for mild cognitive impairment
Helena M Gellersen, Alexandra N Trelle, Benjamin G Farrar, Gillian Theresa Coughlan, Saana Maria Korkki, Richard N Henson, and Jon S Simons
bioRxiv posted 25 May 2022
An automated high-content synaptic phenotyping platform in human neurons and astrocytes reveals a role for BET proteins in synapse assembly
Martin H Berryer, Gizem Rizki, Sara G. Susco, Daisy Lam, Angelica Messana, Darina Trendafilova, Anna Nathanson, Kyle W. Karhohs, Beth A Cimini, Kathleen Pfaff, Anne E Carpenter, Lee L Rubin, and Lindy E Barrett
bioRxiv posted 17 May 2022
Intermittent systemic exposure to lipopolysaccharide-induced inflammation disrupts hippocampal long-term potentiation and impairs cognition in aging male mice
Elizabeth B Engler-Chiurazzi, Ashley E Russell, Jessica M Povroznik, Katherine O McDonald, Keyana Porter, Desheng Wang, Brenda Billig, Christopher Felton, James Hammock, Bernard G Schreurs, James O’Callghan, Kevin Zwezdaryk, and James W Simpkins
bioRxiv posted 18 May 2022
The regulatory landscapes of human ovarian ageing
Yousin Suh, Chen Jin, Xizhe Wang, Adam Hudgins, Amir Gamliel, Mingzhuo Pei, Seungsoo Kim, Daniela Contreras, Jan Hoeijmakers, Judith Campisi, Rogerio Lobo, Zev Williams and Michael G Rosenfeld
bioRxiv posted 19 May 2022
SARS-CoV-2 Infects Peripheral and Central Neurons of Mice Before Viremia, Facilitated by Neuropilin-1
Jonathan D. Joyce, Greyson A. Moore, Poorna Goswami, Emma H. Leslie, Christopher K. Thompson, and Andrea S Bertke
bioRxiv posted 20 May 2022
APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge
Sangderk Lee, Nicholas A Devanney, Lesley R Golden, Cathryn T Smith, James L Schwartz, Adeline E Walsh, Harrison A Clarke, Danielle S Goulding, Elizabeth J Allenger, Gabriella Morillo-Segovia, Cassi M Friday, Amy A Gorman, Tara R Hawkinson, Steven M MacLean, Holden C Williams, Ramon C Sun, Josh M Morganti, and Lance A Johnson
bioRxiv posted 20 May 2022
Brain-muscle connectivity during gait: corticomuscular coherence as quantification of the cognitive reserve
Laura Caffi, Stefano Boccia, Valeria Longatelli, Eleonora Guanziroli, Franco Molteni and Alessandra Laura Giulia Pedrocchi
bioRxiv posted 20 May 2022
Physical resilience in the brain: The effect of white matter disease on brain networks in cognitively normal older adults
Blake R Neyland, Samuel N Lockhart, Robert G Lyday, Laura D Baker, Elizabeth P Handing, Michael E Miller, Stephen B Kritchevsky, Paul J Laurienti, and Christina E Hugenschmidt
bioRxiv posted 24 May 2022
Brain injury accelerates the onset of a reversible age-related microglial phenotype associated with hyperphagocytosis and inflammatory neurodegeneration
Rodney M Ritzel, Yun Li, Yun Jiao, Zhuofan Lei, Sarah J Doran, Junyun He, Rami A Shahror, Rebecca J Henry, Shaolin Liu, Bogdan A Stoica, Alan I Faden, Gregory Szeto, David J Loane, and Junfang Wu
bioRxiv posted 25 May 2022
Bi-phasic patterns of age-related differences in dopamine D1 receptors across the adult lifespan
Jarkko Johansson, Kristin Nordin, Robin Pedersen, Nina Karalija, Goran Papenberg, Micael Andersson, Saana M. Korkki, Katrine Riklund, Marc Guitart-Masip, Anna Rieckmann, Lars Bäckman, Lars Nyberg, and Alireza Salami
bioRxiv posted 25 May 2022
Rapid and precise genome engineering in a naturally short-lived vertebrate
Ravi D. Nath, Claire N. Bedbrook, Rahul Nagvekar, Karl Deisseroth and Anne Brunet
bioRxiv posted 26 May 2022
Reduced memory precision in older age is associated with functional and structural differences in the angular gyrus
Saana M. Korkki, Franziska R. Richter, Helena M. Gellersen, and Jon S. Simons
bioRxiv posted 28 May 2022
Gcm: a novel anti-inflammatory transcriptional cascade conserved from flies to humans
Alexia Pavlidaki, Radmila Panic, Sara Monticelli, Celine Riet, Yoshihiro Yuasa, Pierre B. Cattenoz, Brahim Nait-Oumesmar, and Angela Giangrande
bioRxiv posted 29 May 2022
Age and cognitive load affect muscle activation profiles in response to physical perturbations while walking
Uri Rosenblum, Itshak Melzer, Michael Friger, Gabi Zeilig, and Meir Plotnik
bioRxiv posted 30 May 2022
Topographic Stability and Layer-Specific Flexibility are Mechanisms of Human Cortical Plasticity
Alicia Northall, Juliane Doehler, Miriam Weber, Stefan Vielhaber, Stefanie Schreiber, and Esther Kuehn
bioRxiv posted 30 May 2022
