From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others
Age-related changes in neural synchronization and the sustained response to amplitude and frequency modulation of sound
Bjorn Herrmann, Burkhard Maess, and Ingrid S. Johnsrude
bioRxiv posted 29 April 2022
Deficiency in pericyte remodeling as a basis for impaired capillary flow and structure during brain aging
Andree-Anne Berthiaume, Franca Schmid, Stefan Stamenkovic, Vanessa Santos, Cara Nielson, Bruno Weber, Mark Majesky, and Andy Shih
bioRxiv posted 29 April 2022
Older circuits get richer: neurogenesis timeline shapes hubness and neurogenetic profiles of the adult human brain
Ibai diez, Fernando Garcia Moreno, Nayara Carral Sainz, Sebastiano Stramaglia, Alicia Nieto Reyes, Mauro D’Amato, Jesus M Cortes, and paolo bonifazi
bioRxiv posted 29 April 2022
Global brain health modulates the impact of lesion damage on post-stroke sensorimotor outcomes
Sook-Lei Liew, Nicolas Schweighofer, James H Cole, Artemis Zavaliangos-Petropulu, Bethany P Lo, Laura KM Han, Tim Hahn, Lianne Schmaal, Miranda R Donnelly, Jessica N Jeong, Zhizhuo Wang, Aisha Abdullah, Jun H Kim, Alexandre Hutton, Giuseppe Barisano, Michael R Borich, Lara A Boyd, Amy Brodtmann, Cathrin M Buetefisch, Winston D Byblow, Jessica M Cassidy, Charalambos C Charalambous, Valentina Ciullo, Adriana B Conforto, Rosalia Dacosta-Aguayo, Julie A DiCarlo, Martin Domin, Adrienne N Dula, Natalia Egorova-Brumley, Wuwei Feng, Fatemeh Geranmayeh, Chris M Gregory, Colleen A Hanlon, Jess A Holguin, Brenton Hordacre, Neda Jahanshad, Steven A Kautz, Mohamed Salah Khlif, Hosung Kim, Amy Kuceyeski, David J Lin, Jingchun Liu, Martin Lotze, Bradley J MacIntosh, John L Margetis, Maria Mataro, Feroze B Mohamed, Emily R Olafson, Gilsoon Park, Fabrizio Piras, Kate P Revill, Pamela Roberts, Andrew D Robertson, Nerses Sanoss ian, Heidi M Schambra, Na Jin Seo, Surjo R Soekadar, Gianfranco Spalletta, Cathy M Stinear, Myriam Taga, Wai Kwong Tang, Greg T Thielman, Daniela Vecchio, Nick S Ward, Lars T Westlye, Carolee J Winstein, George F Wittenberg, Steven L Wolf, Kristin A Wong, Chunshui Yu, Steven C Cramer, and Paul Thompson
bioRxiv posted 29 April 2022
Age-related changes of deep-brain neurophysiological activity
Thomas T Hinault, Sylvain T Baillet, and Susan Courtney
bioRxiv posted 28 April 2022
Blood-brain barrier dysfunction promotes astrocyte senescence through albumin-induced TGFβ signaling activation
Marcela Preininger, Dasha Zaytseva, Jessica May Lin, and Daniela Kaufer
bioRxiv posted 28 April 2022
A Quantum Dot Biomimetic for SARS-CoV-2 to Interrogate Dysregulation of the Neurovascular Unit Relevant to Brain Inflammation
Wesley Chiang, Angela Litzburg, Francine Yanchik-Slade, Herman Li, Bradley L. Nilsson, Harris A Gelbard, and Todd D Krauss
bioRxiv posted 22 April 2022
Functional Specialization of Parallel Distributed Networks Revealed by Analysis of Trial-to-Trial Variation in Processing Demands
Lauren M DiNicola, Oluwatobi I Ariyo and Randy L Buckner
bioRxiv. posted 20 April 2022
Fleeting Effects of Incentives: Adult Age Differences in ERP Measures of Motivated Attention
Margot D. Sullivan, Farrah Kudus, Ben Dyson, and Julia Spaniol
bioRxiv posted 18 April 2022
Persistent post-COVID-19 smell loss is associated with inflammatory infiltration and altered olfactory epithelial gene expression
John B Finlay, David H Brann, Ralph Abi Hachem, David W Jang, Allison D Oliva, Tiffany Ko, Rupali Gupta, Sebastian A Wellford, E Ashley Moseman, Sophie S Jang, Carol H Yan, Hiroaki Matsunami, Tatsuya Tsukahara, Sandeep Robert Datta, and Bradley J Goldstein
bioRxiv posted 18 April 2022
A Third Somatomotor Representation in the Human Cerebellum
Noam Saadon-Grosman, Peter A Angeli, Lauren M DiNicola and Randy L Buckner
bioRxiv. posted 14 April 2022
Age-related changes in the neural mechanics of dynamic auditory attention in time
Bjorn Herrmann, Burkhard Maess, Molly J. Henry, Jonas Obleser, and Ingrid S. Johnsrude
bioRxiv posted 13 April 2022
Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons
Maria A Telpoukhovskaia, Niran Hadad, Brianna Gurdon, Miko Dai, Andrew R Ouellette, Sarah M Neuner, Amy R Dunn, Shania Hansen, Yiyang Wu, Logan Dumitrescu, Kristen M.S. O’Connell, Eric B Dammer, Nicholas T Seyfried, Sukalp Muzumdar, Jesse Gillis, Paul Robson, Ji-Gang Zhang, Timothy J. Hohman, Vivek Philip, Vilas Menon and Catherine C Kaczorowski
bioRxiv. posted 13 April 2022
Larger and more dentated hippocampal structure is associated with better memory in the oldest-old.
Vuga Parpura, Hector Caceres, Sara Sims, Lawrence Ver Hoef, Anandh K Ramaniharan, Stacy Merritt, Roxanne F Rezaei, Pradyumna K Bharadwaj, Mary Kate Franchetti, David A Raichlen, Courtney J Jessup, Alex G Hinshaw, Emily J Van Etten, Theodore P Trouard, David S Geldmacher, Virginia G Wadley, Noam Alperin, Eric S Porges, Adam J Woods, Ron A Cohen, Bonnie E Levin, Tatjana Rundek, Gene E Alexander, and Kristina M Visscher
bioRxiv posted 11 April 2022
Life-long Dietary Restrictions have Negligible or Damaging Effects on Late-life Cognitive Performance: A Key Role for Genetics in Outcomes
Andrew R Ouellette, Niran Hadad, Andrew Deighan, Laura Robinson, Kristen M.S. O’Connell, Adam Freund, Gary A Churchill and Catherine Kaczorowski
bioRxiv. posted 10 April 2022
Unexpected proteinopathies in hippocampal PDE11A4 promote age-related cognitive decline of social associative memories
Kaitlyn ( Pilarzyk, Latarsha Porcher, William R. Capell, Steven D. Burbano, Jeffrey Davis, Janet Fisher, Nicole Gorny, Siena Petrolle, and Michy P. Kelly
bioRxiv posted 10 April 2022
Less is more – loss of EGFL7 improves memory by upregulation of VEGF-D
Mirko HH Schmidt, Verica Vasic, Kathrin Barth, Frank Bicker, Ulrike Schumann, Christine Maurer, Nora Heinig, Cora Roehlecke, Ute Nimtschke, Lana Schumann, Matthias Meinhardt, Thomas Mittmann, Konstantin Radyushkin, Jan Baumgart, Stefan Tenzer, Frauke Zipp, and Irmgard Tegeder
bioRxiv posted 10 April 2022
Liver-secreted fluorescent blood plasma markers enable chronic imaging of microcirculation
Xiaowen Wang, Christine Delle, Antonis Asiminas, Sonam Akther, Marta Vittani, Peter Brogger, Peter Kusk, Camilla Trang Vo, Ayumu Konno, Hirokazu Hirai, Masahiro Fukuda, Pia Weikop, Steven Alan Goldman, Maiken Nedergaard and Hajime Hirase
bioRxiv. posted 10 April 2022
DeepParcellation: a novel deep learning method for robust brain magnetic resonance imaging parcellation in older East Asians
Eun-Cheon Lim, Uk-Su Choi, Kyu Yeong Choi, Jang Jae Lee, Yul-Wan Sung, Seiji Ogawa, Byeong Chae Kim, Kun Ho Lee, Jungsoo Gim, and the Alzheimer’s Disease Neuroimaging Initiative
bioRxiv posted 9 April 2022
Cochlear Neurotrophin-3 overexpression at mid-life prevents age-related cochlear synaptopathy and slows age-related hearing loss
Luis R Cassinotti, Lingchao Ji, Beatriz C Borges, Nathan D Cass, Aditi S Desai, David C Kohrman, M. Charles Liberman, and Gabriel Corfas
bioRxiv posted 8 April 2022
A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during ageing and in Alzheimer’s disease
Megan E Jones, Johanna Buechler, Tom Dufor, Katharina Boroviak, Emmanouil Metzakopian, Alasdair Gibb, and Patricia C Salinas
bioRxiv posted 8 April 2022
Microglia Detect Externalized Phosphatidylserine on Synapses for Elimination via TREM2 in Alzheimer’s Disease Models
Javier Rueda-Carrasco, Dimitra Sokolova, Sang-Eun Lee, Thomas Childs, Natalia Jurcakova, Sebastiaan De Schepper, Judy Z. Ge, Joanne I. Lachica, Christina E. Toomey, Oliver J. Freeman, John Hardy, Beth Stevens, Tammaryn Lashley, Sunghoe Chang and Soyon Hong
bioRxiv. posted 5 April 2022
Affective enhancement of episodic memory is associated with widespread patterns of intrinsic functional connectivity across the adult lifespan
Yuta Katsumi and Matthew Moore
bioRxiv posted 1 April 2022
The role of clearance in neurodegenerative diseases
Georgia S Brennan, Travis B Thompson, Hadrien Oliveri, Marie E Rognes, and Alain Goriely
bioRxiv posted 1 April 2022
History of previous midlife estradiol treatment permanently alters interactions of brain insulin-like growth factor-1 signaling and hippocampal estrogen synthesis to enhance cognitive aging in a rat model of menopause
Nina E Baumgartner, Shannon M McQuillen, Samantha F Perry, Sangtawan Miller, Robert Gibbs and Jill M Daniel
bioRxiv. posted 1 April 2022
