From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others
A comparison of intracranial volume estimation methods and their cross-sectional and longitudinal associations with age
Stener Nerland, Therese S. Stokkan, Kjetil N. Jørgensen, Laura A. Wortinger, Geneviève Richard, Dani Beck, Dennis van der Meer, Lars T. Westlye, Ole A. Andreassen, Ingrid Agartz, and Claudia Barth
bioRxiv posted 30 March 2022
Age-related differences in functional network segregation in the context of sex and reproductive stage
Hannah K. Ballard, T. Bryan Jackson, Abigail C. Miller, Tracey H. Hicks, and Jessica A. Bernard
bioRxiv posted 29 March 2022
LTD-inducing low frequency stimulation enhances p-Tau181 and p-Tau217 in an age-dependent manner in live rats
Neng-Wei Hu, Yangyang Zhang, Yin Yang, Zhengtao Hu, Manyi Zhu, Shuangying Qin, Pengpeng Yu, Bo Li, Jitian Xu, and Michael J Rowan
bioRxiv posted 29 March 2022
T cells induce interferon-responsive oligodendrocytes during white matter aging
Tugberk Kaya, Nicola Mattugini, Lu Liu, Hao Ji, Simon Besson-Girard, Seiji Kaji, Arthur Liesz, Ozgun Gokce, and Mikael Simons
bioRxiv posted 27 March 2022
Subjective cognitive decline predicts lower cingulo-opercular network functional connectivity in individuals with lower neurite density in the forceps minor
Adriana L Ruiz-Rizzo, Raymond P Viviano, Ana M Daugherty, Kathrin Finke, Hermann J Mueller, and Jessica S Damoiseaux
bioRxiv posted 27 March 2022
Structural and functional MRI data differentially predict chronological age and behavioral memory performance
Joram Soch, Anni Richter, Jasmin M Kizilirmak, Hartmut Schütze, Hannah Feldhoff, Larissa Fischer, Lea Knopf, Matthias Raschick, Annika Schult, Emrah Düzel, and Björn H Schott
bioRxiv posted 27 March 2022
The Rise and Fall of Slow Wave Tides: Vacillations of Slow Wave/Spindle Coupling Shift the Composition of Slow Wave Activity Through Sleep Cycles in Accordance with Depth of Sleep
Brice V McConnell, Eugene Kronberg, Lindsey M Medenblik, Vitaly O Kheyfets, Alberto R Ramos, Stefan H Sillau, Rachelle L Pulver, and Brianne M Bettcher
bioRxiv posted 25 March 2022
Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages
Amirhossein Modabbernia, Didac Vidal-Pineiro, Ingrid Agartz, Ole A Andreassen, Rosa Ayesa-Arriola, Alessandro Bertolino, Dorret I Boomsma, Josiane Bourque, Alan Breier, Rachel M Brouwer, Jan K Buitelaar, Erick J Canales-Rodriguez, Xavier Caseras, Patricia J Conrod, Benedicto Crespo-Facorro, Fabrice Crivello, Eveline A Crone, Greig I de Zubicaray, Erin W Dickie, Danai Dima, Stefan Frenzel, Simon E. Fisher, Barbara Franke, David C Glahn, Hans-Jorgen Grabe, Dominik Grotegerd, Oliver Gruber, Amalia Guerrero-Pedraza, Raquel E Gur, Ruben C Gur, Catharina A Hartman, Pieter J Hoekstra, Hilleke E Hulshoff Pol, Neda Jahanshad, Terry L Jernigan, Jiyang Jiang, Andrew J Kalnin, Nicole A Kochan, Bernard Mazoyer, Brenna C McDonald, Katie L McMahon, Lars Nyberg, Jaap Oosterlaan, Edith Pomarol-Clotet, Joaquim Radua, Perminder S Sachdev, Theodore D Satterthwaite, Raymond Salvador, Salvador Sarro, Andrew J Saykin, Gunter Schuma nn, Jordan W Smoller, Iris E Sommer, Thomas Espeseth, Sophia I Thomopoulos, Julian N Trollor, Dennis van ‘t Ent, Aristotle Voineskos, Yang Wang, Bernd Weber, Wei Wen, Lars T Westlye, Heather C Whalley, Steven CR Williams, Katharina Wittfeld, Margaret J Wright, Paul M Thompson, Thomas Paus, and Sophia Frangou
bioRxiv posted 22 March 2022
SARS-CoV-2 spike proteins uptake mediated by lipid raft ganglioside GM1 in human cerebrovascular cells
Conor McQuaid, Alexander Solorzano, Ian Dickerson, and Rashid Deane
bioRxiv posted 21 March 2022
Effects of habitual dart training on hemispheric lateralization in older adults: a cross-sectional study using functional near-infrared spectroscopy
Koki Toyofuku, Satoru Hiwa, Kensuke Tanioka, Tomoyuki Hiroyasu, and Masaki Takeda
bioRxiv posted 20 March 2022
Timely sleep coupling: spindle-slow wave synchrony is linked to early amyloid-β burden and predicts memory decline
Daphne Chylinski, Maxime Van Egroo, Justinas Narbutas, Vincenzo Muto, Mohamed Ali Bahri, Christian Berthomier, Eric Salmon, Christine Bastin, Christophe Phillips, Fabienne Collette, Pierre Maquet, Julie Carrier, Jean-Marc Lina, and Gilles Vandewalle
bioRxiv posted 19 March 2022
Patterns of retrieval-related cortico-striatal connectivity are stable across the adult lifespan
Paul F Hill, Marianne de Chastelaine, and Michael D Rugg
bioRxiv posted 18 March 2022
A correlational study between microstructural, macrostructural and functional age-related changes in the human visual cortex
Hamid Abrishami Moghaddam, Sahar Rahimi Malakshan and Farveh Daneshvarfard
bioRxiv. posted 17 March 2022, 10.1101/2022.03.17.484772
Age-dependent lipid droplet-rich microglia worsen stroke outcome in old mice
Maria Arbaizar-Rovirosa, Mattia Gallizioli, Jordi Pedragosa, Juan J Lozano, Carme Casal, Albert Pol, and Anna M Planas
bioRxiv posted 16 March 2022
Individualized Gaussian Process-based Prediction of Memory Performance and Biomarker Status in Ageing and Alzheimer’s disease
Aditya Nemali, Niklas Vockert, David Berron, Anne Maas, Renat Yakupov, Oliver Peters, Daria Gref, Nicoleta Cosma, Lukas Preis, Josef Priller, Eike Jakob Spruth, Slawek Altenstein, Andrea Lohse, Klaus Fliessbach, Okka Kimmich, Ina Vogt, Jens Wiltfang, Niels Hansen, Claudia Bartels, Björn H. Schott, Franziska Maier, Dix Meiberth, Wenzel Glanz, Enise Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Lena Burow, Stefan Teipel, Ingo Kilimann, Doreen Göerß, Martin Dyrba, Christoph Laske, Matthias H. Munk, Carolin Sanzenbacher, Stephan Müller, Annika Spottke, Nina Roy, Michael T. Heneka, Frederic Brosseron, Sandra Röske, Laura Dobisch, Alfredo Ramirez, Michael Ewers, Peter Dechent, Klaus Scheffler, Luca Kleineidam, Steffen Wolfsgruber, Michael Wagner, Frank Jessen, Emrah Düzel, and Gabriel Ziegler
bioRxiv posted 16 March 2022
Impairments in fear extinction memory and basolateral amygdala plasticity in the TgF344-AD rat model of Alzheimer’s disease are distinct from non-pathological aging.
Caesar M Hernandez, III, Nateka L Jackson, Abbi R Hernandez, and Lori L McMahon
bioRxiv posted 14 March 2022
Associations between locus coeruleus MRI contrast and physiological responses to acute stress in younger and older adults
Shelby L Bachman, Kaoru Nashiro, Hyunjoo Yoo, Diana Wang, Julian F Thayer, and Mara Mather
bioRxiv posted 14 March 2022
A Microengineered Brain-Chip to Model Neuroinflammation in Humans
Iosif Pediaditakis, Konstantia R. Kodella, Dimitris V. Manatakis, Christopher Y. Le, Sonalee Barthakur, Alexander Sorets, Achille Gravanis, Lorna Ewart, Lee L. Rubin, Elias S. Manolakos, Chris D. Hinojosa and Katia Karalis
bioRxiv. posted 14 March 2022
Co-release of histamine and GABA in prefrontal cortex excites fast-spiking interneurons and causes divisive gain change in pyramidal cells; an effect that is enhanced in older mice
Diana Lucaci, Xiao Yu, Paul Chadderton, William Wisden, and Stephen G Brickley
bioRxiv posted 13 March 2022
The maternal X chromosome impairs cognition and accelerates brain aging through epigenetic modulation in female mice
Samira Abdulai-Saiku, Shweta Gupta, Dan Wang, Arturo Moreno, Yu Huang, Deepak Srivastava, Barbara Panning, and Dena Dubal
bioRxiv posted 12 March 2022
NLGC: Network Localized Granger Causality with Application to MEG Directional Functional Connectivity Analysis
Behrad Soleimani, Proloy Das, I.M. Dushyanthi Karunathilake, Stefanie E. Kuchinsky, Jonathan Z. Simon, and Behtash Babadi
bioRxiv posted 11 March 2022
Sensory Tetanization to Induce LTP-Like Plasticity: A Review and Reassessment of the Approach
James W. Dias, Carolyn M. McClaskey, Jeffrey A. Rumschlag, and Kelly C. Harris
bioRxiv posted 9 March 2022
Skeletal Muscle Proteostasis Promotes Central Nervous System Rejuvenation and Reduces Neuroinflammation during Aging and Neurodegenerative Disease
Ian Matthews, Allison Birnbaum, Anastasia Gromova, Kristen Coutinho, Megan McGraw, Dalton Patterson, Macy T Banks, Amber Nobles, Helen C Miranda, Albert R La Spada, and Constanza J Cortes
bioRxiv posted 8 March 2022
Impaired peri-olfactory Cerebrospinal Fluid clearance mediated cognitive decline after dyssomnia
Ying Zhou, Wang Ran, Zhongyu Luo, Jianan Wang, Mengmeng Fang, Kai Wei, Jianzhong Sun, and Min Lou
bioRxiv posted 7 March 2022
Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain
Pierre Lemaitre, Samar Tareen, Emanuela Pasciuto, Loriana Mascali, Araks Martirosyan, Zsuzsanna Callaerts-Vegh, James Dooley, Matthew Holt, Lidia Yshii, and Adrian Liston
bioRxiv posted 4 March 2022
Identification of protein aggregates in the aging vertebrate brain with prion-like andphase separation properties
Itamar Harel, Yiwen R. Chen, Inbal Ziv, Param Priya Singh, Paloma Navarro Negredo, Uri Goshtchevsky, Wei Wang, Gwendoline Astre, Eitan Moses, Andrew McKay, Ben E. Machado, Katja Hebestreit, Sifei Yin, Alejandro Sanchez Alvarado, Daniel F Jarosz, and Anne Brunet
bioRxiv posted 1 March 2022
Influence of age and cognitive performance on resting-state functional connectivity of dopaminergic and noradrenergic centres
Michal Rafal Zareba, Wiktoria Furman, and Marek Binder
bioRxiv posted 1 March 2022
Tissue-specific landscape of protein aggregation and quality control in an aging vertebrate
Yiwen R. Chen, Itamar Harel, Param Priya Singh, Inbal Ziv, Eitan Moses, Uri Goshtchevsky, Ben E. Machado, Anne Brunet and Daniel F. Jarosz
bioRxiv. posted 1 March 2022