From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others
Age differences in aperiodic neural activity measured with resting EEG
Ashley Merkin, Sabrina Sghirripa, Lynton Graetz, Ashleigh E Smith, Brenton Hordacre, Richard Harris, Julia Pitcher, John Semmler, Nigel C Rogasch and Mitchell Goldsworthy
bioRxiv. posted 1 September 2021
http://biorxiv.org/content/early/2021/09/01/2021.08.31.458328
The Digital Brain Bank, an open access platform for post-mortem datasets
Benjamin C. Tendler, Taylor Hanayik, Olaf Ansorge, Sarah Bangerter-Christensen, Gregory S. Berns, Mads F. Bertelsen, Katherine L. Bryant, Sean Foxley, Martijn van den Heuvel, Amy F.D. Howard, Istvan Huszar, Alexandre A. Khrapitchev, Anna Leonte, Paul R. Manger, Ricarda A.L. Menke, Jeroen Mollink, Duncan Mortimer, Menuka Pallebage-Gamarallage, Lea Roumazeilles, Jerome Sallet, Lianne H. Scholtens, Connor Scott, Adele Smart, Martin R. Turner, Chaoyue Wang, Saad Jbabdi, Rogier B. Mars and Karla L. Miller
bioRxiv. posted 22 June 2021
http://biorxiv.org/content/early/2021/09/01/2021.06.21.449154
Cell types and clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics
Michael Ratz, Leonie von Berlin, Ludvig Larsson, Marcel Martin, Jakub Orzechowski Westholm, Gioele La Manno, Joakim Lundeberg and Jonas Frisen
bioRxiv. posted 1 September 2021
http://biorxiv.org/content/early/2021/09/01/2021.08.31.458418
Weakly activated core inflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer’s disease
Fuhai Li, Abdallah Eteleeb, William Buchser, Guoqiao Wang, Chengjie Xiong, Philip R. Payne, Eric McDade, Celeste M. Karch, Oscar Harari and Carlos Cruchaga
bioRxiv. posted 1 September 2021
http://biorxiv.org/content/early/2021/09/01/2021.08.30.458295
Differential regulation of mouse hippocampal gene expression sex differences by chromosomal content and gonadal sex
Sarah R Ocanas, Victor A Ansere, Kyla B Tooley, Niran Hadad, Ana J Chucair-Elliott, David R Stanford, Shannon Rice, Benjamin Wronowski, Jessica M Hoffman, Steven N Austad, Michael B Stout and Willard M Freeman
bioRxiv. posted 2 September 2021
http://biorxiv.org/content/early/2021/09/02/2021.09.01.458115
MOSCATO: A Supervised Approach for Analyzing Multi-Omic Single-Cell Data
Lorin M Towle-Miller and Jeffrey C Miecznikowski
bioRxiv. posted 4 September 2021
http://biorxiv.org/content/early/2021/09/04/2021.09.02.458781
Neural circuit dynamics of drug-context associative learning in the hippocampus
Yanjun Sun and Lisa M Giocomo
bioRxiv. posted 5 September 2021
http://biorxiv.org/content/early/2021/09/05/2021.09.02.458796
Global Mapping of Mouse CSF Flow via HEAP-METRIC Phase-contrast MRI
Juchen Li, Mengchao Pei, Binshi Bo, Xinxin Zhao, Jing Cang, Fang Fang and Zhifeng Liang
bioRxiv. posted 6 September 2021
http://biorxiv.org/content/early/2021/09/06/2021.09.04.459006
Ascertaining cells’ synaptic connections and RNA expression simultaneously with massively barcoded rabies virus libraries
Arpiar Saunders, Kee Wui Huang, Cassandra Vondrak, Christina Hughes, Karina Smolyar, Harsha Sen, Adrienne C Philson, James Nemesh, Alec Wysoker, Seva Kashin, Bernardo L Sabatini and Steven A McCarroll
bioRxiv. posted 6 September 2021
http://biorxiv.org/content/early/2021/09/06/2021.09.06.459177
Real Age Prediction from the Transcriptome with RAPToR
Romain Bulteau and Mirko Francesconi
bioRxiv. posted 8 September 2021
http://biorxiv.org/content/early/2021/09/08/2021.09.07.459270
Microglia drive pockets of neuroinflammation in middle age
Eric N. Moca, Daniela Lecca, Keenan T. Hope, David Tweedie, Shanaya Sidhu, Lindsay Masukawa, Hannah Sitoy, Rose Mathew, Daniel R. Saban, Nigel H. Greig, Lindsay M. De Biase
https://www.biorxiv.org/content/10.1101/2021.02.02.429070v2
Lipid chaperone LBP-8 coordinates with nuclear factors to promote longevity in Caenorhabditis elegans
Jonathon Duffy, Qinghao Zhang, Sung Y Jun and Meng C Wang
bioRxiv. posted 9 September 2021
http://biorxiv.org/content/early/2021/09/09/2021.09.09.459489
Distinct and diverse chromatin-proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions
Giorgio Oliviero, Sergey Kovalchuk, Adelina Rogowska-Wrzesinska, Veit Schwämmle and Ole N. Jensen
bioRxiv. posted 12 September 2021
http://biorxiv.org/content/early/2021/09/12/2021.09.09.459706
Activation of the CaMKII-Sarm1-ASK1 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria
Chen Ding, Youjun Wu, Hadas Dabas and Marc Hammarlund
bioRxiv. posted 12 September 2021
http://biorxiv.org/content/early/2021/09/12/2021.09.12.459970
Reduced plasticity in coupling strength in the SCN clock in aging as revealed by Kuramoto modelling
Anouk Willemijn van Beurden, Janusz Meylahn, Stefan Achterhof, Johanna Meijer and Jos Rohling
bioRxiv. posted 14 September 2021
http://biorxiv.org/content/early/2021/09/14/2021.09.13.460004
Proximal CA3 is the primary locus of age-related pattern separation deficits in rats
Heekyung Lee, Arjuna Tilekeratne, Nick Lukish, Zitong Wang, Scott Zeger, Michela Gallagher and James J Knierim
bioRxiv. posted 16 September 2021
http://biorxiv.org/content/early/2021/09/16/2021.09.14.460329
Longitudinal effects of using and discontinuing CNS medications on cognitive functioning
Elise Koch, Kristina Johnell and Karolina Kauppi
bioRxiv. posted 16 September 2021
http://biorxiv.org/content/early/2021/09/16/2021.09.13.460082
Lifelong musical activity is associated with multi-domain cognitive and brain benefits in older adults
Adriana Boettcher, Alexis Zarucha, Theresa Koebe, Malo Gaubert, Angela Hoeppner, Klaus Fabel, Slawek Altenstein, Claudia Bartels, Katharina Buerger, Peter Dechent, Laura Dobisch, Michael Ewers, Klaus Fliessbach, Silka Dawn Freiesleben, Ingo Frommann, John-Dylan Haynes, Daniel Janowitz, Ingo Kilimann, Luca Kleineidam, Christoph Laske, Franziska Maier, Coraline Metzger, Matthias Munk, Robert Perneczky, Oliver Peters, Josef Priller, Boris-Stephan Rauchmann, Nina Roy, Klaus Scheffler, Anja Schneider, Annika Spottke, Stefan J. Teipel, Steffen Wolfsgruber, Jens Wiltfang, Renat Yakupov, Emrah Duzel, Frank Jessen, Sandra Roeske, Michael Wagner, Gerd Kempermann, Miranka Wirth and DELCODE study group
bioRxiv. posted 17 September 2021
http://biorxiv.org/content/early/2021/09/17/2021.09.15.460202
Adiponectin receptor agonist AdipoRon improves skeletal muscle function in aged mice
Priya Balasubramanian, Anne E Schaar, Grace E Gustafson, Alex B Smith, Porsha R Howell, Angela Greenman, Scott Baum, Ricki J Colman, Dudley W Lamming, Gary M Diffee and Rozalyn Anderson
bioRxiv. posted 17 September 2021
http://biorxiv.org/content/early/2021/09/17/2021.09.16.460597
High-order functional interactions in ageing explained via alterations in the connectome in a whole-brain model
Marilyn Gatica, Fernando E. Rosas, Pedro A.M. Mediano, Ibai Diez, Stephan P. Swinnen, Patricio Orio, Rodrigo Cofre and Jesus M. Cortes
bioRxiv. posted 17 September 2021
http://biorxiv.org/content/early/2021/09/17/2021.09.15.460435
Regulation of the cognitive aging process by the transcriptional repressor RP58
Tomoko Tanaka, Shinobu Hirai, Hiroyuki Manabe, Kentaro Endo, Hiroko Shimbo and haruo okado
bioRxiv. posted 20 September 2021
http://biorxiv.org/content/early/2021/09/20/2021.09.18.460879
Characterizing the human methylome across the life course: findings from eight UK-based studies
Esther Walton, Riccardo Marioni, Hannah R Elliott, Simon R Cox, Ian R Deary, Alun D Hughes, Therese Tillin, Meena Kumari, Tom Woofenden, Juan E Castillo-Fernandez, Jordana Tzenova Bell, Alissa Goodman, George Ploubidis, Kate Tilling, Matthew Suderman, Tom R Gaunt, Erin C Dunn, Andrew Smith and Caroline Relton
bioRxiv. posted 20 September 2021
http://biorxiv.org/content/early/2021/09/20/2021.09.18.460916
The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia
Ralda Nehme, Olli Pietilainen, Mykyta Artomov, Matthew Tegtmeyer, Christina Bell, Andrea Ganna, Tarjinder Singh, Aditi Trehan, Vera Valakh, John Sherwood, Danielle Manning, Emily Peirent, Rhea Malik, Ellen J. Guss, Derek Hawes, Amanda Beccard, Anne M. Bara, Dane Z. Hazelbaker, Emanuela Zuccaro, Giulio Genovese, Alexander A. Loboda, Anna Neumann, Christina Lilliehook, Outi Kuismin, Eija Hamalainen, Mitja Kurki, Christina M. Hultman, Anna K. Kahler, Joao A. Paulo, Jon Madison, Bruce Cohen, Donna McPhie, Rolf Adolfsson, Roy Perlis, Ricardo Dolmetsch, Samouil Farhi, Steven McCarroll, Steven Hyman, Ben Neale, Lindy E. Barrett, Wade Harper, Aarno Palotie, Mark Daly and Kevin Eggan
bioRxiv. posted 22 September 2021
http://biorxiv.org/content/early/2021/09/22/2021.09.22.461360
White matter hyperintensities may be an early marker for age-related cognitive decline in the ADNI cohort
Cassandra Morrison, Mahsa Dadar, Sylvia Villeneuve and D. Louis Collins
bioRxiv. posted 24 September 2021
http://biorxiv.org/content/early/2021/09/24/2021.09.23.461560
A network model of glymphatic flow under different experimentally-motivated parametric scenarios
Jeffrey Tithof, Kimberly A. S. Boster, Peter A. R. Bork, Maiken Nedergaard, John H. Thomas and Douglas H. Kelley
bioRxiv. posted 24 September 2021
http://biorxiv.org/content/early/2021/09/24/2021.09.23.461519
Aging reduces calreticulin expression and alters spontaneous calcium signals in astrocytic endfeet of the mouse dorsolateral striatum
Sara M. Zarate, Taylor E. Huntington, Pooneh Bagher, and Rahul Srinivasan
bioRxiv posted 25 September 2021
https://www.biorxiv.org/content/10.1101/2021.09.24.461710
Pyramidal cell types drive functionally distinct cortical activity patterns during decision-making
Simon Musall, Xiaonan Richard Sun, Hemanth Mohan, Xu An, Steven Gluf and Anne K. Churchland
bioRxiv. posted 27 September 2021
http://biorxiv.org/content/early/2021/09/27/2021.09.27.461599
