From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others
Cortical thickness, gray matter volume and cognitive performance: a cross-sectional study of the moderating effects of age on their inter-relationships
Marianne de Chastelaine, Sabina Srokova, Mingzhu Hou, Amber Kidwai, Seham Kafafi, Melanie Racenstein, and Michael Rugg
bioRxiv posted 2 October 2022
A single-cell multi-omic atlas spanning the adult rhesus macaque brain
Kenneth L Chiou, Xingfan Huang, Martin O Bohlen, Sebastien Tremblay, Diana R O’Day, Cailyn H Spurrell, Aishwarya A Gogate, Trisha M Zintel, Cayo Biobank Research Unit, Madeline G Andrews, Melween I Martinez, Lea M Starita, Michael J Montague, Michael L Platt, Jay Shendure and Noah Snyder-Mackler
bioRxiv. posted 3 October 2022
Motor imagery training is beneficial for motor memory of upper and lower limb tasks in very old adults
Pauline M Hilt, Mathilde Bertrand, Leonard Feasson, Florent Lebon, France Mourey, Celia Ruffino, and Vianney Rozand
bioRxiv posted 4 October 2022
The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice
Luke D Roberts, Amanda K. E. Hornsby, Alanna Thomas, Martina Sassi, Aimee Kinzett, Nathan Hsiao, Bethan R David, Mark Good, Timothy Wells, and Jeffrey S Davies
bioRxiv posted 6 October 2022
The vertical position of visual information conditions spatial memory performance in healthy aging
Marion Durteste, Louise Van Poucke, Sonia Combariza, Bilel Abderrahmane Benziane, José-Alain Sahel, Stephen Ramanoël, and Angelo Arleo
bioRxiv posted 7 October 2022
Free-water volume fraction increases non-linearly with age in the white matter of the healthy human brain
Tomasz Pieciak, Guillem París, Dani Beck, Ivan Maximov, Antonio Tristán-Vega, Rodrigo de Luis-García, Lars T. Westlye, and Santiago Aja-Fernández
bioRxiv posted 7 October 2022
Optic radiations representing different eccentricities age differently
John Kruper, Noah C Benson, Sendy Caffarra, Julia P Owen, Yue Wu, Aaron Y Lee, Cecilia S Lee, Jason D Yeatman, and Ariel Rokem
bioRxiv posted 7 October 2022
GABA decrease is associated with degraded neural specificity in the visual cortex of glaucoma patients
Ji Won Bang, Carlos Parra, Kevin Yu, Gadi Wollstein, Joel Schuman, and Kevin Chan
bioRxiv posted 12 October 2022
Exome-wide analysis reveals role of LRP1 and additional novel loci in cognition
Shreya Chakraborty and Bratati Kahali
bioRxiv. posted 14 October 2022
Network Segregation in Aging Females and Evaluation of the Impact of Sex Steroid Hormones
Tracey H Hicks, Thamires N.C. Magalhaes, Hannah K Ballard, T. Bryan Jackson, Sydney J. Cox, and Jessica A. Bernard
bioRxiv posted 16 October 2022
Electrophysiological signatures of targeted memory reactivation during sleep are not accompanied by motor performance improvements in older adults
Judith Nicolas, Julie Carrier, Stephan Swinnen, Julien Doyon, Genevieve Albouy, and Bradley Ross King
bioRxiv posted 17 October 2022
The integrity of dopaminergic and noradrenergic brain regions is associated with different aspects of late-life memory performance
Martin J. Dahl, Shelby L Bachman, Shubir Dutt, Sandra Duezel, Nils C. Bodammer, Ulman Lindenberger, Simone Kuehn, Markus Werkle-Bergner, and Mara Mather
bioRxiv posted 17 October 2022
Myeloid deficiency of the intrinsic clock protein Bmal1 accelerates cognitive aging by disrupting microglial synaptic pruning
Chinyere Agbaegbu Iweka, Erica Michelle Seigneur, Amira Latif Hernandez, Sur Herrera Paredes, Mica Cabrera, Eran Blacher, Connie Pasternak, Frank Longo, Luis de Lecea and Katrin Andreasson
bioRxiv. posted 18 October 2022
Facilitatory stimulation of the pre-SMA in healthy aging has distinct effects on task-based activity and connectivity
Sandra Martin, Regine Frieling, Dorothee Saur, and Gesa Hartwigsen
bioRxiv posted 21 October 2022
Inherent envelope fluctuations in forward masking: Effects of age and hearing loss
Marc Brennan, Adam Svec, Afagh Farhadi, Braden Maxwell, and Laurel H Carney
bioRxiv posted 21 October 2022
Facilitatory stimulation of the pre-SMA in healthy aging has distinct effects on task-based activity and connectivity
Sandra Martin, Regine Frieling, Dorothee Saur and Gesa Hartwigsen
bioRxiv. posted 21 October 202
Persistent Homology-based Functional Connectivity Explains Cognitive Ability: Life-span Study
Hyunnam Ryu, Christian G Habeck, Yaakov Stern, and Seonjoo Lee
bioRxiv posted 21 October 2022
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies
Ariel K Frame, J. Wesley Robinson, Nader H. Mahmoudzadeh, Jason M. Tennessen, Anne F. Simon, and Robert C. Cumming
bioRxiv posted 21 October 2022
Adult lifespan trajectories of neuromagnetic signals and interrelations with cortical thickness
Christina Stier, Christoph Braun, and Niels K. Focke
bioRxiv posted 24 October 2022
LTP-like noninvasive striatal brain stimulation enhances striatal activity and motor skill learning in humans
Maximilian J. Wessel, Elena Beanato, Traian Popa, Fabienne Windel, Pierre Vassiliadis, Pauline Menoud, Valeriia Beliaeva, Ines R. Violante, Hedjoudje Abderrahmane, Patrycja Dzialecka, Chang-Hyun Park, Pablo Maceira-Elvira, Takuya Morishita, Antonino Cassara, Melanie Steiner, Nir Grossman, Esra Neufeld, and Friedhelm C. Hummel
bioRxiv posted 28 October 2022
Chronic intermittent propofol attenuates surgery-induced neuroinflammation, apoptosis, and cognitive impairment in aged mice
Rajasekar Nagarajan, Jinrui Lyu, Maltesh Kambali, Muxiao Wang, Robert A. Pearce, and Uwe Rudolph
bioRxiv posted 28 October 2022
Mixed Models Quantify Annual Volume Change; Linear Regression Determines Thalamic Volume as the Best Subcortical Structure Volume Predictor in Alzheimer’s Disease and Aging
Charles S Leger, Monique Herbert, W Dale Stevens, and Joseph F DeSouza
bioRxiv posted 31 October 2022
Transcription, structure, and organoids translate time across the lifespan of humans and great apes
Christine J Charvet, Kwadwo Ofori, Carmen Falcone, and Brier A Rigby Dames
bioRxiv posted 31 October 2022
Aging impairs astrocytes in the human cerebral cortex
Alexander Popov, Nadezda Brazhe, Kseniia Morozova, Konstantin Yashin, Maxim Bychkov, Olga Nosova, Oksana Sutyagina, Alexey Brazhe, Evgenia Parshina, Li Li, Igor Medyanik, Dmitry E Korzhevskii, Zakhar Shenkarev, Ekaterina Lyukmanova, Alexei Verkhratsky, and Alexey Semyanov
bioRxiv posted 1 November 2022
Genetic ablation of dentate hilar somatostatin-positive GABAergic interneurons is sufficient to induce cognitive impairment
Rajasekar Nagarajan, Jinrui Lyu, Maltesh Kambali, Muxiao Wang, Connor D. Courtney, Catherine A. Christian-Hinman, and Uwe Rudolph
bioRxiv posted 2 November 2022
Integrated Multi-Omics Analysis of Brain Aging in Female Nonhuman Primates Reveals Altered Signaling Pathways Relevant to Age-Related Disorders
Laura A Cox, Sobha Puppala, Jeannie Chan, Kip Zimmerman, Zeeshan Hamid, Isaac Ampong, Hillary F Huber, Ge Li, Avinash YL Jadhav, Benlian Wang, Cun Li, Carol Shively, Geoffrey Clarke, Thomas C Register, Peter W Nathanielsz and Michael Olivier
bioRxiv. posted 2 November 2022
A generalizable epigenetic clock captures aging in two nonhuman primates.
Elisabeth A Goldman, Marina M Watowich, Kenneth L Chiou, Arianne Mercer, Sierra N Sams, Julie E Horvath, Jordan Anderson, Cayo Biobank Research Unit, Jenny Tung, James P Higham, Lauren JN Brent, Melween I Martinez, Michael James Montague, Michael L Platt, Kirstin N Sterner and Noah Snyder-Mackler
bioRxiv. posted 2 November 2022
Network Occlusion Sensitivity Analysis Identifies Regional Contributions to Brain Age Prediction
Lingfei He, Cheng Chen, Yaping Wang, Qingcheng Fan, Congying Chu, Junhai Xu, and Lingzhong Fan
bioRxiv posted 3 November 2022
Age-related changes in brain metabolites underlie slowing of speed-accuracy trade-off
Lauren Revie and Claudia Metzler-Baddeley
bioRxiv posted 3 November 2022
Musical expertise enhances neural alignment-to-young in sensorimotor regions that predicts older adults’ audiovisual speech-in-noise perception
Lei Zhang, Xiuyi Wang, and Yi Du
bioRxiv posted 5 November 2022
Neural Entrainment to Musical Pulse In Naturalistic Music Is Preserved In Aging: Implications for Music-Based Interventions
Parker Tichko, Nicole Page, Ji Chul Kim, Edward Large, and Psyche Loui
bioRxiv posted 6 November 2022
Age-related changes in ‘cortical’ 1/f dynamics are explained by cardiac activity
Fabian Schmidt, Sarah K. Danboeck, Eugen Trinka, Gianpaolo Demarchi, and Nathan Weisz
bioRxiv posted 7 November 2022
Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex
Masashi Fujita, Zongmei Gao, Lu Zeng, Cristin McCabe, Charles C White, Bernard Ng, Gilad Sahar Green, Orit Rozenblatt-Rosen, Devan Phillips, Liat Amir-Zilberstein, Hyo Lee, Richard V Pearse II, Atlas Khan, Badri N Vardarajan, Krzysztof Kiryluk, Chun Jimmie Ye, Hans-Ulrich Klein, Gao Wang, Aviv Regev, Naomi Habib, Julie A Schneider, Yanling Wang, Tracy Young-Pearse, Sara Mostafavi, David A Bennett, Vilas Menon and Phillip L De Jager
bioRxiv. posted 8 November 2022
Investigation of the neural effects of memory training to reduce false memories in older adults: Univariate and multivariate analyses
Indira C Turney, Jordan D Chamberlain, Jonathan G Hakun, Ashley C Steinkrauss, Lesley A Ross, Brenda A Kirchhoff, and Nancy A Dennis
bioRxiv posted 9 November 2022 [Abstract] [PDF]
Estimation of Vertex-wise Sulcal Width Maps on Cortical Surfaces
Alberto Fernandez-Pena, Francisco J. Navas-Sanchez, Daniel Martin de Blas, Luis Marcos-Vidal, Pedro M. Gordaliza, Isabel Martinez-Tejada, Joost Janssen, Susanna Carmona, Manuel Desco, and Yasser Aleman-Gomez
bioRxiv posted 9 November 2022
Epigenetic age acceleration predicts subject-specific white matter degeneration in the human brain.
Benjamin T Newman, Joshua S Danoff, Morgan E Lynch, Stephanie Giamberardino, Simon G Gregory, Jessica J Connelly, T Jason Druzgal, and James P Morris
bioRxiv posted 14 November 2022
Brain-age prediction: a systematic comparison of machine learning workflows
Shammi More, Georgios Antonopoulos, Felix Hoffstaedter, Julian Caspers, Simon B. Eickhoff, and Kaustubh R. Patil
bioRxiv posted 17 November 2022
Multi-‘Omic Integration via Similarity Network Fusion to Detect Molecular Subtypes of Aging
Mu Yang, Stuart Matan-Lithwick, Yanling Wang, Phillip De Jager, David A Bennett and Daniel Felsky
bioRxiv. posted 17 November 2022
Neural noise is associated with age-related neural dedifferentiation
Rachelle E Pichot, Daniel J. Henreckson, Morgan Foley, and Joshua D Koen
bioRxiv posted 18 November 2022
BrainAGE revisited: Keeping up the pace with deep learning methods
Polona Kalc, Robert Dahnke, Felix Hoffstaedter, and Christian Gaser
bioRxiv posted 22 November 2022
Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)
Courtney Glavis-Bloom, Casey R Vanderlip, Sammy Weiser Novak, Masaaki Kuwajima, Lyndsey Kirk, Uri Manor, Kristen M Harris, and John H Reynolds
bioRxiv posted 28 November 2022
Openness to experience is associated with neural and performance measures of memory in older adults
Christopher Stolz, Ariane Bulla, Joram Soch, Bjoern Hendrik Schott, and Anni Richter
bioRxiv posted 29 November 2022
