From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others

Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.

How synchrony and metastable network dynamics are affected in fast and slow timescales with aging: Implication for Cognition

Priyanka Chakraborty, Shubham Kumar, Amit Naskar, Arpan Banerjee, and Dipanjan Roy

bioRxiv posted 30 November 2021

[Abstract] [PDF]

 

OViTAD: Optimized Vision Transformer to Predict Various Stages of Alzheimer’s Disease Using Resting-State fMRI and Structural MRI Data

Saman Sarraf, Arman Sarraf, Danielle D. DeSouza, John A. E. Anderson, Milton Kabia, and The Alzheimer’s Disease Neuroimaging Initiative ADNI

bioRxiv posted 29 November 2021

[Abstract] [PDF]

 

White Matter Hyperintensity Distribution Differences in Aging and Neurodegenerative Disease Cohorts

Mahsa Dadar, Sawsan Mahmoud, Maryna Zhernovaia, Richard Camicioli, Josefina Maranzano, and Simon Duchesne

bioRxiv posted 27 November 2021

[Abstract] [PDF]

 

Association between plasma phospho-tau181 and cognitive change from age 73 to 82: Lothian Birth Cohort 1936

Tyler S Saunders, Amanda Heslegrave, Declan King, Sarah Harris, Craig W Ritchie, Graciela Muniz-Terrera, Ian J Deary, Simon R Cox, Henrik Zetterberg, and Tara Spires-Jones

bioRxiv posted 25 November 2021

[Abstract] [PDF]

 

Population-level asymmetry of the cerebral cortex: reproducibility, lifespan changes, heritability, and individual differences

James M Roe, Didac Vidal-Pineiro, Inge K Amlien, Mengyu Pan, Markus H Sneve, Michel Thiebaut de Schotten, Patrick Friedrich, Zhiqiang Sha, Clyde H Francks, Yunpeng Wang, Kristine B Walhovd, Anders M Fjell, and Rene Westerhausen

bioRxiv posted 25 November 2021

[Abstract] [PDF]

 

Age Differences in Diffusivity in the Locus Coeruleus and its Ascending Noradrenergic Tract

Shai Porat, Francesca Sibilia, Josephine Yoon, Yonggang Shi, Martin J. Dahl, Markus Werkle-Bergner, Sandra Duzel, Nils Bodammer, Ulman Lindenberger, Simone Kuhn, and Mara Mather

bioRxiv posted 24 November 2021

[Abstract] [PDF]

 

In vitro and in vivo CRISPR-Cas9 screens reveal drivers of aging in neural stem cells of the brain

Tyson J Ruetz, Chloe M Kashiwagi, Bhek Morton, Robin W Yeo, Dena S Leeman, David W Morgens, C Kimberly Tsui, Amy Li, Michael C Bassik, and Anne Brunet

bioRxiv posted 23 November 2021

[Abstract] [PDF]

 

Estradiol and oxytocin modulate sex differences in hippocampal reactivity and episodic memory

Marie Coenjaerts, Isabelle Trimborn, Berina Adrovic, Birgit Stoffel-Wagner, Larry Cahill, Alexandra Philipsen, Rene Hurlemann and Dirk Scheele

bioRxiv posted 22 November 2021

[Abstract]

 

The effect of external stimulation on functional networks in the aging healthy human brain

Anira Escrichs, Yonatan Sanz Perl, Noelia Martinez-Molina, Carles Biarnes, Josep Garre, Jose Manuel Fernandez-Real, Rafel Ramos, Ruth Marti, Reinald Pamplona, Ramon Brugada, Joaquin Serena, Lluis Ramio-Torrenta, Gabriel Coll, Lluis Gallart, Jordi Barretina, Joan Vilanova, Jordi Mayneris-Perxachs, Luca Saba, Salvador Pedraza, Morten L Kringelbach, Josep Puig, and Gustavo Deco

bioRxiv posted 20 November 2021

[Abstract] [PDF]

 

Age-dependent increased sag current in human pyramidal neurons dampens baseline cortical activity

Alexandre Guet-McCreight, Homeira Moradi Chameh, Sara Mahallati, Margaret Wishart, Shreejoy J Tripathy, Taufik A Valiante, and Etay Hay

bioRxiv posted 19 November 2021

[Abstract] [PDF]

 

The sleep EEG envelope: a novel, neuronal firing-based human biomarker

Peter Przemyslaw Ujma, Martin Dresler, Peter Simor, Daniel Fabo, Istvan Ulbert, Lorand Eross, and Robert Bodizs

bioRxiv posted 19 November 2021

[Abstract] [PDF]

 

MTD: a unique pipeline for host and meta-transcriptome joint and integrative analyses of RNA-seq data

Fei Wu, Yao-Zhong Liu and Binhua Ling

bioRxiv posted 19 November 2021

[Abstract]

 

Trajectory of rich club properties in structural brain networks

Levin Riedel, Martijn P van den Heuvel, and Sebastian Markett

bioRxiv posted 19 November 2021

[Abstract] [PDF]

 

Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia

Aurelie Bussy, Jake Levy, Raihaan Patel, Lani Cupo, Tristin Best, Tim Van Langenhove, Jorgen Nielsen, Yolande Pijnenburg, Maria Landqvist Waldö, Anne Remes, Matthias L Schroeter, Isabel Santana, Florence Pasquier, Markus Otto, Adrian Danek, Johannes Levin, Isabelle Le Ber, Rik Vandenberghe, Matthis Synofzik, Fermin Moreno, Alexandre de Mendonca, Raquel Sanchez-Valle, Robert Laforce, Tobias Langheinrich, Alexander Gerhard, Caroline Graff, Chris R. Butler, Sandro Sorbi, Lize Jiskoot, Harro Seelaar, John C. van Swieten, Elizabeth Finger, Maria Carmela Tartaglia, Mario Masellis, Pietro Tiraboschi, Daniela Galimberti, Barbara Borroni, James Rowe, Martina Bocchetta, Jonathan D. Rohrer, Gabriel A. Devenyi, M. Mallar Chakravarty, and Simon Ducharme

bioRxiv posted 16 November 2021

[Abstract] [PDF]

 

Apolipoprotein ε4 modifies obesity-related atrophy in the hippocampal formation of cognitively healthy adults

Bethany M. Coad, Parisa A. Ghomroudi, Rebecca Sims, John P. Aggleton, Seralynne D. Vann and Claudia Metzler-Baddeley

bioRxiv posted 16 November 2021

[Abstract]

 

The overlapping modular organization of human brain functional networks across the adult lifespan

Yue Gu, Liangfang Li, Yining Zhang, Junji Ma, Chenfan Yang, Yu Xiao, Shu Ni, Ying Lin, and Zhengjia Dai

bioRxiv posted 13 November 2021

[Abstract] [PDF]

 

Age-linked suppression of lipoxin A4 mediates cognitive deficits in mice and humans

Fabrício A. Pamplona, Gabriela Vitória, Felipe C. Ribeiro, Carolina A. Moraes, Pitia F. Ledur, Karina Karmirian, Isis M. Ornelas, Luciana M. Leo, Bruna Paulsen, Felipe K. Sudo, Gabriel Coutinho, Claudia Drummond, Naima Assuncão, Bart Vanderborght, Claudio Canetti, Hugo C. Castro-Faria-Neto, Paulo Mattos, Sergio T. Ferreira, Stevens K. Rehen, Fernando A. Bozza, Mychael V. Lourenco, and Fernanda Tovar-Moll

bioRxiv posted 13 November 2021

[Abstract] [PDF]

 

Cerebral blood flow predicts multiple demand network activity and fluid intelligence across the lifespan

Shuyi Wu, Lorraine K. Tyler, Richard N.A. Henson, James B. Rowe, Cam-Can and Kamen A. Tsvetanov

bioRxiv posted 13 November 2021

[Abstract]

 

Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation.

Macarena S Arrázola, Matías Lira, Gabriel Quiroz, Somya Iqbal, Samantha L Eaton, Rachel A Kline, Douglas J Lamont, Hernán Huerta, Gonzalo Ureta, Sebastian Bernales, J César Cárdenas, Waldo Cerpa, Thomas M Wishart, and Felipe A Court

bioRxiv posted 11 November 2021

[Abstract] [PDF]

 

Age-dependent formation of TMEM106B amyloid filaments in human brain

Manuel Schweighauser, Diana Arseni, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Kathy L Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Benjamin Falcon, Alexey G Murzin, Michel Goedert, and Sjors Scheres

bioRxiv posted 11 November 2021

[Abstract] [PDF]

 

Natural variation in gene expression and Zika virus susceptibility revealed by villages of neural progenitor cells

Michael F Wells, James Nemesh, Sulagna Ghosh, Jana M Mitchell, Curtis J Mello, Daniel Meyer, Kavya Raghunathan, Matthew Tegtmeyer, Derek Hawes, Anna Neumann, Kathleen A Worringer, Joseph J Raymond, Sravya Kommineni, Karrie Chan, Daniel Ho, Brant K Peterson, Federica Piccioni, Ralda F Nehme, Kevin Eggan and Steven A McCarroll

bioRxiv posted 9 November 2021

[Abstract]

 

Differential relationships between brain structure and dual task walking in young and older adults

Kathleen Hupfeld, Justin Geraghty, Heather R McGregor, Chris J Hass, Ofer Pasternak, and Rachael Seidler

bioRxiv posted 5 November 2021

[Abstract] [PDF]

 

Age-dependent Effect Imposed by Rotenone Exposure

Madeleine C Moseley, Ashley Rawls, Valerie M Sponsel, Mitchel S Berger, Adam R Abate, and CHIN HSING ANNIE LIN

bioRxiv posted 4 November 2021

[Abstract] [PDF]

 

Age-Volume Associations in Cerebellar Regions by Sex and Reproductive Stage

Tracey H Hicks, Hannah K Ballard, Huiyan Sang, and Jessica A Bernard

bioRxiv posted 4 November 2021

[Abstract] [PDF]

 

Conservation and divergence in cortical cellular organization between human and mouse revealed by single-cell transcriptome imaging

Rongxin Fang, Chenglong Xia, Meng Zhang, Jiang He, Jennie Close, Brian Long, Jeremy Miller, Ed Lein, and Xiaowei Zhuang

bioRxiv posted 2 November 2021

[Abstract] [PDF]

 

Effects of upgrading acquisition-techniques and harmonization methods: A multi-modal MRI study with implications for longitudinal designs

Takashi Itahashi, Yuta Y. Aoki, Ayumu Yamashita, Takafumi Soda, Junya Fujino, Haruhisa Ohta, Ryuta Aoki, Motoaki Nakamura, Nobumasa Kato, Saori C. Tanaka, Daisuke Kokuryo, and Ryu-ichiro Hashimoto

bioRxiv posted 2 November 2021

[Abstract] [PDF]

 

Explaining heterogeneity in medial entorhinal cortex with task-driven neural networks

Aran Nayebi, Alexander Attinger, Malcolm G. Campbell, Kiah Hardcastle, Isabel I.C. Low, Caitlin S. Mallory, Gabriel C. Mel, Ben Sorscher, Alex H. Williams, Surya Ganguli, Lisa M. Giocomo and Daniel L.K. Yamins

bioRxiv posted 2 November 2021

[Abstract]

 

Age-related response speed deficits arise from specific impairments in sensory evidence accumulation rate

Meadhbh B. Brosnan, Megan H O’Neill, Gerard M Loughnane, Daniel J Pearce, Bryce Fleming, Trevor T.J. Chong, Anna Christina Nobre, Redmond G O’Connell, and Mark A Bellgrove

bioRxiv posted 1 November 2021

[Abstract] [PDF]

 

Tracking neural activity from the same cells during the entire adult life of mice

Siyuan Zhao, Xin Tang, Sebastian Partarrieu, Shiqi Guo, Ren Liu, Jaeyong Lee, Zuwan Lin, and Jia Liu

bioRxiv posted 1 November 2021

[Abstract] [PDF]

 

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