Exploring Cancer Drivers and Dependencies
- Speaker
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Scott W. Lowe, Ph.D.Chair, Geoffrey Beene Cancer Research Center, Memorial Sloan-Kettering Cancer Center
Presidential Lectures are free public colloquia centered on four main themes: Biology, Physics, Mathematics and Computer Science, and Neuroscience and Autism Science. These curated, high-level scientific talks feature leading scientists and mathematicians and are intended to foster discourse and drive discovery among the broader NYC-area research community. We invite those interested in the topic to join us for this weekly lecture series.
The human body contains gene networks that naturally inhibit tumor development. This defensive arsenal includes repairing damaged DNA, suppressing inflammation and triggering the self-destruction of cells.
In this lecture, Scott W. Lowe will discuss his lab’s work exploring how the genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response and create vulnerabilities that may be targeted therapeutically. He will outline how his team combines genetic, genomic and animal model approaches to comprehensively study cancer biology. He will also discuss tumor-suppressor gene networks and strategies to restore their function in advanced cancers.
About the Speaker
Lowe is the chair of the Cancer Biology and Genetics Program at Memorial Sloan Kettering Cancer Center (MSKCC) and investigator in the Howard Hughes Medical Institute. He received his B.S. from the University of Wisconsin-Madison, and his Ph.D. from the Massachusetts Institute of Technology. Before joining MSKCC, Lowe was a faculty member at Cold Spring Harbor Laboratory in New York. He is a member of the American Academy of Arts and Sciences and the National Academy of Sciences.